4670-10-4

Basic information

• Product Name: 3,5-DIMETHOXYPHENYLACETIC ACID
• Synonyms: 3,5-DIMETHOXYPHENYLACETIC ACID;RARECHEM AL BO 0339;TIMTEC-BB SBB006648;3,5-Dimethoxy;(3,5-Dimethoxyphenyl)acetic acid,98%;Benzeneacetic acid, 3,5-diMethoxy-;3,5-Dimethoxybenzeneacetic acid;(3,5-Dimethoxyphenyl)acetic acid 98%
• CAS NO: 4670-10-4
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Product Categories: Aromatic Phenylacetic Acids and Derivatives;Organic acids;Building Blocks for Dendrimers;Functional Materials;C10;Carbonyl Compounds;Carboxylic Acids
• Mol File: 4670-10-4.mol
• Article Data: 23

Chemical Properties

• Melting Point: 102-103 °C(lit.)
• Boiling Point: 293.08°C (rough estimate)
• Flash Point: 140.1 °C
• Appearance: brown powder
• Density: 1.2166 (rough estimate)
• Vapor Pressure: 1.4E-05mmHg at 25°C
• Refractive Index: 1.5430 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.08±0.10(Predicted)
• CAS DataBase Reference: 3,5-DIMETHOXYPHENYLACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHOXYPHENYLACETIC ACID(4670-10-4)
• EPA Substance Registry System: 3,5-DIMETHOXYPHENYLACETIC ACID(4670-10-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36/37
• Safety Statements: 26-36-36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 4670-10-4(Hazardous Substances Data)

Usage

Chemical Properties

brown powder

Uses

3,5-Dimethoxyphenylacetic Acid is a general reactant/reagent used in the synthesis of a recyclable, immobilized analogue of Benzotetramisole.

General Description

(3,5-Dimethoxyphenyl)acetic acid is a carboxylic acid. Its physical properties like density, freezing point, boiling point and refractive index have been determined.

InChI:InChI=1/C10H12O4/c1-13-8-3-7(5-10(11)12)4-9(6-8)14-2/h3-4,6H,5H2,1-2H3,(H,11,12)/p-1

Upstream product

• 39151-19-4 1-(3,5-dimethoxyphenyl)ethan-1-one 
• 365564-07-4 3,5-dimethoxyphenylboronic acid pinacol ester 
• 1141493-97-1 tert-butyl 2-(3,5-dimethoxyphenyl)acetate 
• 124-38-9 carbon dioxide 
• 56723-83-2 2-(3,5-dimethoxyphenyl)nitroethane 
• 86255-43-8 trans-1-(3,5-Dimethoxyphenyl)-2-nitroethylene 
• 4179-19-5 1,3-dimethoxy-5-methylbenzene 
• 64118-89-4 Methoxyeugenol 
• 2150-37-0 methyl 3,5-dimethoxybenzoate 
• 17213-57-9 3,5-dimethoxybenzoyl chloride 
• 4670-09-1 2-(3,5-dihydroxyphenyl)acetic acid 
• 4724-10-1 methyl 2-(3,5-dihydroxyphenyl)acetate 
• 6652-32-0 3,5-dimethoxybenzylchloride 
• 7311-34-4 3,5-dimethoxybenzaldehdye 

Downstream Products

• 18917-77-6 (3,5-dimethoxyphenyl)acetone 
• 7417-20-1 3,5-dimethoxyphenethyl alcohol 
• 65976-77-4 (3,5-dimethoxy-phenyl)-acetic acid ethyl ester 
• 81280-93-5 benzoin 3,5-dimethyloxyphenyl acetate 
• 39500-08-8 α-(3,5-Dimethoxyphenyl)-3-hydroxy-4-methoxyzimtsaeure 
• 17275-78-4 2-Brom-3,5-dimethoxy-phenylessigsaeure-methylester 
• 17275-81-9 2,6-Dibrom-3,5-dimethoxy-phenylessigsaeure-methylester 
• 93324-50-6 2.4.-Dinitro-α-<3.5-dimethoxy-phenyl>-zimtsaeure 
• 1025686-80-9 1-methyl-4-pentenyl (3,5-dimethoxyphenyl)acetate 
• 537-42-8 3,5-dimethoxy-4'-hydroxy-trans-stilbene 
• 135387-93-8 (S)-3-[(S)-2-Azido-2-(3,5-dimethoxy-phenyl)-acetyl]-4-benzyl-oxazolidin-2-one 
• 103889-87-8 (S)-3,5-dimethoxyphenylglycine 
• 103889-85-6 (R)-3,5-dimethoxyphenylglycine 
• 1092105-45-7 (1R,3S)-(3,5-dimethoxyphenyl)acetic acid 3-(tert-butyldimethylsilanyloxy)-1-methylhex-5-enyl ester 

Relevant articles and documents

Desulfonylative Electrocarboxylation with Carbon Dioxide

Electrocarboxylation of organic halides is one of the most investigated electrochemical approaches for converting thermodynamically inert carbon dioxide (CO2) into value-added carboxylic acids. By converting organic halides into their sulfone derivatives, we have developed a highly efficient electrochemical desulfonylative carboxylation protocol. Such a strategy takes advantage of CO2as the abundant C1 building block for the facile preparation of multifunctionalized carboxylic acids, including the nonsteroidal anti-inflammatory drug ibuprofen, under mild reaction conditions.

Stereoselective Total Synthesis of (-)-(2 S,4 R)-3′-Methoxyl Citreochlorol: Preparation and Use of New Proline-Based Auxiliary for Asymmetric Acetate Aldol Reaction

The first stereoselective total synthesis of (-)-(2S,4R)-3′-methoxy citreochlorol and (-)-(2S,4S)-3′-methoxy citreochlorol is demonstrated. A proline-based imidazolidinone was synthesized and used as chiral auxiliary for asymmetric acetate aldol reaction to generate initial chirality in the targeted molecule. Geminal dichloromethane functionality was introduced by the addition of in situ generated dichloromethyllithium to Weinreb's amide functional group.

Simple access to 5-carboalkoxy-2,3-dihydro-4H-pyran-4-ones via domino acylative electrocyclization: The first three step total synthesis of the dihydronaphthopyran-4-one class of natural products

Intermolecular domino C-acylation/6π-oxaelectrocyclization between β-ketoesters and α,β-unsaturated acid chlorides took place readily in the presence of CaCl2 to afford a variety of polysubstituted 5-carboalkoxy-2,3-dihydro-4H-pyran-4-ones, in good yields. The products were successfully exploited as precursors, for a simple and efficient construction of a naphthalene fused pyran-4-one ring system. This intramolecular Friedel-Crafts acylative aromatization approach was useful for the synthesis of the phytogrowth inhibiting dihydronaphthopyranone class of natural products.