Technology Process of 6-((6-(3,4-dichlorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline
There total 5 articles about 6-((6-(3,4-dichlorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: selenium(IV) oxide / 1,4-dioxane / 5 h / Reflux
1.2: 1 h / Reflux
2.1: toluene-4-sulfonic acid / ethanol / 4 h / 20 °C
2.3: 4 h / 60 °C
3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1.5 h / 20 °C
3.2: 5 h / 20 °C
4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C
5.1: acetic acid / 4 h / 100 °C
With
selenium(IV) oxide; benzotriazol-1-ol; toluene-4-sulfonic acid; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid;
In
1,4-dioxane; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2016.03.076
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / ethanol / 4 h / 20 °C
1.3: 4 h / 60 °C
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1.5 h / 20 °C
2.2: 5 h / 20 °C
3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C
4.1: acetic acid / 4 h / 100 °C
With
benzotriazol-1-ol; toluene-4-sulfonic acid; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid;
In
ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2016.03.076
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1.5 h / 20 °C
1.2: 5 h / 20 °C
2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C
3.1: acetic acid / 4 h / 100 °C
With
benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2016.03.076
