2642-63-9

Basic information

• Product Name: 3',4'-DICHLOROACETOPHENONE
• Synonyms: 1-(3,4-DICHLOROPHENYL)ETHAN-1-ONE;1-(3,4-DICHLOROPHENYL)ETHANONE;3',4'-DICHLOROACETOPHENONE;3,4-DICHLOROACETOPHENONE;AKOS BBS-00003230;1-(3,4-dichlorophenyl)-ethanon;Acetophenone, 3',4'-dichloro-;3',4'-Dichloroacetophenone 1-(3,4-Dichlorophenyl)ethanone 3,4-Dichloroacetophenone
• CAS NO: 2642-63-9
• Molecular Formula: C₈H₆Cl₂O
• Molecular Weight: 189.04
• EINECS: 220-146-0
• Product Categories: Acetophenone Series;Aromatic Acetophenones & Derivatives (substituted);Adehydes, Acetals & Ketones;Chlorine Compounds;C7 to C8;Carbonyl Compounds;Ketones;Aromatics;Miscellaneous Reagents
• Mol File: 2642-63-9.mol
• Article Data: 20

Chemical Properties

• Melting Point: 72-74 °C(lit.)
• Boiling Point: 135 °C12 mm Hg(lit.)
• Flash Point: 134-135mm°C/12mm
• Appearance: white to cream-colored powder or crystals
• Density: 1.2979 (rough estimate)
• Refractive Index: 1.5595 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 742534
• CAS DataBase Reference: 3',4'-DICHLOROACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3',4'-DICHLOROACETOPHENONE(2642-63-9)
• EPA Substance Registry System: 3',4'-DICHLOROACETOPHENONE(2642-63-9)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36/37/39-36-36/37
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 2642-63-9(Hazardous Substances Data)

Usage

Chemical Properties

white to cream-colored cryst. powder or crystals

Uses

Different sources of media describe the Uses of 2642-63-9 differently. You can refer to the following data:
1. 3'',4''-Dichloroacetophenone (cas# 2642-63-9) is a compound useful in organic synthesis.
2. 3′,4′-Dichloroacetophenone (3,4-Dichloroacetophenone) was used in the synthesis of substituted aryl aminothiazoles.

Upstream product

• 75-36-5 acetyl chloride 
• 95-50-1 1,2-dichloro-benzene 
• 105-56-6 ethyl 2-cyanoacetate 
• 151169-75-4 3,4-dichlophenylboronic acid 
• 99-91-2 para-chloroacetophenone 
• 42981-08-8 2,3',4'-trichloroacetophenone 
• 431-03-8 dimethylglyoxal 
• 95-76-1 m,p-dichloroaniline 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 74877-07-9 1-(S)-(-)-(3,4-dichlorophenyl)-ethylamine 
• 556112-20-0 3,4-dichlorophenylacetylene 
• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 855929-69-0 acetic acid-(6-acetyl-3-chloro-2-nitro-anilide) 
• 96228-48-7 2-acetamido-4-chloro-5-nitroacetophenone 

Downstream Products

• 70374-06-0 (E)-3-Benzo[1,3]dioxol-5-yl-1-(3,4-dichloro-phenyl)-propenone 
• 59826-47-0 3,4-dichlorochalcone 
• 98042-28-5 α,α-dibromo-3',4'-dichloroacetophenone 
• 569656-08-2 N-[5-(3,4-dichloro-phenyl)-2H-pyrazol-3-yl]4,4,4-trifluoro-3-oxo-butyramide 
• 861965-17-5 1-(3,4-dichlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one 
• 909301-59-3 3-chloro-3-(3,4-dichlorophenyl)-2-propenenitrile 

Relevant articles and documents

Promoting charge separation in donor-acceptor conjugated microporous polymers: Via cyanation for the photocatalytic reductive dehalogenation of chlorides

Conjugated microporous polymers (CMPs) have emerged as promising heterogeneous photocatalysts for organic transformations owing to their structural designability and functional versatility. However, limited by the insufficient separation of the photo-generated excitons, their photocatalytic efficiency falls far short of expectations. Herein, we demonstrate a cyanation strategy to promote charge carrier separation in CMPs by selectively incorporating carbazole and cyano groups as electron-donating and electron-withdrawing units, respectively. The resulting CMPs feature π-extended donor (D)-acceptor (A) conjugation structures endowing them with distinct semiconducting properties, in which the efficient charge separation and transfer and wide visible-light absorption are facilitated. Compared to the cyano-free counterpart, the cyano-functionalized CMPs showed superior photocatalytic efficiency as exemplified by photocatalytic reductive dehalogenation of chlorides. More prominently, full recyclability of the designed CMPs as well as catalytic activity for at least ten runs without the loss of catalytic performance in photocatalytic reductive dehalogenation of chlorides demonstrated their robustness and sustainability. This journal is

V2O5@TiO2 Catalyzed Green and Selective Oxidation of Alcohols, Alkylbenzenes and Styrenes to Carbonyls

The versatile application of different functional groups such as alcohols (1° and 2°), alkyl arenes, and (aryl)olefins to construct carbon-oxygen bond via oxidation is an area of intense research. Here, we report a reusable heterogeneous V2O5@TiO2 catalyzed selective oxidation of various functionalities utilizing different mild and eco-compatible oxidants under greener reaction conditions. The method was successfully applied for the alcohol oxidation, oxidative scission of styrenes, and benzylic C?H oxidation to their corresponding aldehydes and ketones. The utilization of mild and eco-friendly oxidizing reagents such as K2S2O8, H2O2 (30 % aq.), TBHP (70 % aq.), broad substrate scope, gram-scale synthesis, and catalyst recyclability are notable features of the developed protocol.

Biomimetic Oxidative Deamination Catalysis via ortho-Naphthoquinone-Catalyzed Aerobic Oxidation Strategy

An ortho-naphthoquinone-catalyzed oxidative deamination reaction has been developed where the molecular oxygen and water serve as the sole oxidant and nucleophile. The current aerobic deamination reaction proceeds via the ketimine formation between ortho-naphthoquinones and amines followed by the prototropic rearrangement and hydrolysis by water, representing a biomimetic oxidative deamination of amine species in the human body by the liver and kidneys. The compatibility of ortho-naphthoquinone organocatalysts with molecular oxygen and water opens up a new biomimetic catalyst system that can function as versatile deaminases for a variety of amine-containing molecules such as amino acids and DNA nuclear bases.