N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide

Base Information

• Chemical Name: N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide
• CAS No.: 858469-67-7
• Molecular Formula: C₁₉H₂₇N₃O₅
• Molecular Weight: 377.44
• Mol file: 858469-67-7.mol

Synonyms:

Chemical Property of N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide

There total 8 articles about N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzoyl-aspartic acid anhydride (39741-36-1) → N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide (858469-67-7)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol

2: triethylamine; dioxane; CHCl₃ / anschliessendes Behandeln mit Glycin-hexylamid

3: aqueous Na₂CO₃

With 1,4-dioxane; ethanol; chloroform; sodium carbonate; triethylamine;

DOI:10.1039/jr9550000259

Reference yield:

N-benzoyl-DL-aspartic acid-4-ethyl ester (779354-17-5) → N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide (858469-67-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine; dioxane; CHCl₃ / anschliessendes Behandeln mit Glycin-hexylamid

2: aqueous Na₂CO₃

With 1,4-dioxane; chloroform; sodium carbonate; triethylamine;

DOI:10.1039/jr9550000259

Reference yield:

benzoyl chloride (98-88-4) → N-(N-benzoyl-DL-α-aspartyl)-glycine hexylamide (858469-67-7)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous K₂CO₃; dioxane

2: triethylamine; dioxane; CHCl₃ / anschliessendes Behandeln mit Glycin-hexylamid

3: aqueous Na₂CO₃

With 1,4-dioxane; chloroform; sodium carbonate; potassium carbonate; triethylamine;

DOI:10.1039/jr9550000259

upstream raw materials:

N-(O-ethyl-N-benzoyl-DL-α-aspartyl)-glycine hexylamide

N-(O-ethyl-N-benzoyl-DL-β-aspartyl)-glycine hexylamide

Gly-NHC₆H₁₃*HCl

N-benzoyl-aspartic acid anhydride