N-(2-nitrobenzyl)-4-ethylaminothiazolidine

Base Information

• Chemical Name: N-(2-nitrobenzyl)-4-ethylaminothiazolidine
• CAS No.: 110822-09-8
• Molecular Formula: C₁₂H₁₇N₃O₂S
• Molecular Weight: 267.352
• Mol file: 110822-09-8.mol

Synonyms:

Chemical Property of N-(2-nitrobenzyl)-4-ethylaminothiazolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-nitrobenzyl)-4-ethylaminothiazolidine

There total 2 articles about N-(2-nitrobenzyl)-4-ethylaminothiazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitrophenylmethyl bromide (3958-60-9) → N-(2-nitrobenzyl)-4-ethylaminothiazolidine (110822-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) K₂CO₃ / 1.) 50percent aq. EtOH, reflux, 10 min; 2.) reflux, 4 h.

2: 1.) POCl₃ / 1.) 110 grad C, 10 min; 2.) CH₂Cl₂, room temp., 1.5 h.

With potassium carbonate; trichlorophosphate;

DOI:10.1002/jhet.5570240122

Reference yield:

N-(2-nitrobenzyl)thiazolidine-4-carboxylic acid (110822-06-5) + ethylamine (75-04-7,85404-22-4) → N-(2-nitrobenzyl)-4-ethylaminothiazolidine (110822-09-8)

Guidance literature:

With trichlorophosphate; Yield given. Multistep reaction; 1.) 110 grad C, 10 min; 2.) CH₂Cl₂, room temp., 1.5 h.;

DOI:10.1002/jhet.5570240122

upstream raw materials:

N-(2-nitrobenzyl)thiazolidine-4-carboxylic acid

ethylamine

2-nitrophenylmethyl bromide