3-Deoxyzinnolide

Base Information

• Chemical Name: 3-Deoxyzinnolide
• CAS No.: 17811-32-4
• Molecular Formula: C15H18 O4
• Molecular Weight: 262.306
• Mol file: 17811-32-4.mol

Synonyms:1(3H)-Isobenzofuranone,4-methoxy-5-methyl-6-[(3-methyl-2-butenyl)oxy]- (9CI); Phthalide,4-methoxy-5-methyl-6-[(3-methyl-2-butenyl)oxy]- (8CI);6-[(3',3'-Dimethylallyl)oxy]-4-methoxy-5-methylphthalide

Chemical Property of 3-Deoxyzinnolide

Chemical Property:

• Vapor Pressure: 3.05E-08mmHg at 25°C
• Boiling Point: 448.6°Cat760mmHg
• Flash Point: 200.7°C
• PSA: 44.76000
• Density: 1.141g/cm³
• LogP: 3.01900

Purity/Quality:

98% ^*data from raw suppliers

3-Deoxyzinnolide ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Deoxyzinnolide

There total 21 articles about 3-Deoxyzinnolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

silvaticol (17811-36-8) + prenyl bromide (870-63-3) → 4-methoxy-5-methyl-6-((3-methylbut-2-en-1-yl)oxy)isobenzofuran-1(3H)-one (17811-32-4)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 24h; Inert atmosphere; Reflux;

DOI:10.1039/c7gc00917h

Reference yield: 87.9%

zinnolide → 4-methoxy-5-methyl-6-((3-methylbut-2-en-1-yl)oxy)isobenzofuran-1(3H)-one (17811-32-4)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; for 1h; Ambient temperature;

DOI:10.1271/bbb1961.49.2811

Reference yield: 73.0%

4-hydroxy-5-methyl-6-(3-methyl-2-butenyloxy)-phthalide (75238-32-3) + methyl p-toluene sulfonate (80-48-8) → 4-methoxy-5-methyl-6-((3-methylbut-2-en-1-yl)oxy)isobenzofuran-1(3H)-one (17811-32-4)

Guidance literature:

With potassium carbonate; In acetone; for 18h; Heating;

DOI:10.1016/S0040-4020(01)93696-8

upstream raw materials:

methyl 2-formyl-3-methoxy-4-methyl-5-(3-methyl-2-butenyloxy)benzoate

4-hydroxy-5-methyl-6-(3-methyl-2-butenyloxy)-phthalide

methyl p-toluene sulfonate

zinniol

Downstream raw materials:

2-hydroxymethyl-3-methoxy-4-methyl-5-(3-methyl-but-2-enyloxy)-benzoic acid

zinniol diacetate

zinniol