1-propyl-1H-indole-3-carboxylic acid

Base Information

Chemical Name:1-propyl-1H-indole-3-carboxylic acid
CAS No.:141102-07-0
Molecular Formula:C12H13NO2
Molecular Weight:203.23700
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10592764
Wikidata:Q82487044
Mol file:141102-07-0.mol

Synonyms:1-propyl-1H-indole-3-carboxylic acid;141102-07-0;1H-Indole-3-carboxylic acid, 1-propyl-;1-propylindole-3-carboxylic acid;SCHEMBL5065671;DTXSID10592764;BKSKGOOUSZXLEC-UHFFFAOYSA-N;1-n-propylindole-3-carboxylic acid;STL432252;AKOS000262989;DB-337394;CS-0251369;EN300-54518;G25335;AP-970/43507309;Z335290252

Suppliers and Price of 1-propyl-1H-indole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-propyl-1H-indole-3-carboxylicacid
250mg
$ 310.00

Labseeker
1H-INDOLE-3-CARBOXYLICACID,1-PROPYL- 95
25g
$ 3208.00

American Custom Chemicals Corporation
1-PROPYL-1H-INDOLE-3-CARBOXYLIC ACID 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
1-PROPYL-1H-INDOLE-3-CARBOXYLIC ACID 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
1-PROPYL-1H-INDOLE-3-CARBOXYLIC ACID 95.00%
1G
$ 852.55

AK Scientific
1-Propyl-1H-indole-3-carboxylicacid
250mg
$ 248.00

AK Scientific
1-Propyl-1H-indole-3-carboxylicacid
500mg
$ 382.00

Total 3 raw suppliers

Chemical Property of 1-propyl-1H-indole-3-carboxylic acid

Chemical Property:

PSA：42.23000
LogP:2.74950
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:203.094628657
Heavy Atom Count:15
Complexity:242

Purity/Quality:

99% ^*data from raw suppliers

1-propyl-1H-indole-3-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1C=C(C2=CC=CC=C21)C(=O)O

Technology Process of 1-propyl-1H-indole-3-carboxylic acid

There total 5 articles about 1-propyl-1H-indole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 858515-83-0
1-propylindole-3-carboxylic acid methyl ester

: 141102-07-0
1-propyl-1H-indole-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2005.04.002

Reference yield:

: 942-24-5
3-methoxycarbonylindole

: 141102-07-0
1-propyl-1H-indole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / methanol; tetrahydrofuran

With sodium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2005.04.002

Reference yield:

: 771-50-6
1H-indole-3-carboxylic acid

: 141102-07-0
1-propyl-1H-indole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuric acid / 8 h / 0 °C / Reflux

2.1: sodium hydride / tetrahydrofuran / 0 - 20 °C

2.2: 12 h / 20 °C

3.1: sodium hydroxide / tetrahydrofuran; methanol; water / 7 h / 70 °C

3.2: pH 2

With sulfuric acid; sodium hydride; sodium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1039/c6md00255b