942-24-5Relevant articles and documents
A New Method for the Synthesis of 3-Substituted Indoles
Natarajan, Rakesh,Rappai, John P.,Unnikrishnan, Peruparampil A.,Radhamani, Sandhya,Prathapan, Sreedharan
supporting information, p. 2467 - 2471 (2015/10/19)
Starting from readily accessible nitrones and electron-deficient acetylenes, a highly efficient and versatile synthetic protocol for 3-substituted indoles has been developed.
Simple, fast and efficient synthesis of β-keto esters from the esters of heteroaryl compounds, its antimicrobial study and cytotoxicity towards various cancer cell lines
Venkat Ragavan,Vijayakumar,Rajesh,Palakshi Reddy,Karthikeyan,Suchetha Kumari
supporting information; experimental part, p. 4193 - 4197 (2012/07/14)
A series of β-keto esters were synthesized from heteroaryl esters and ethyl acetate using LiHMDS as base at -50 to -30 °C. The increase in yields of cross condensed product were observed and the percentage of self condensed product was reduced drastically by applying the suitable base (LiHMDS), solvent and the minimum amount of ethyl acetate. All these β-keto esters were characterized using 1H NMR, 13C NMR and mass spectral data. A plausible mechanism is also depicted to prove the formation of trans-esterified products. All the synthesized compounds were subjected to test for their cytotoxicity towards various cancer cell lines and also tested for their antimicrobial activity towards various bacterial and fungal strains and some of them were found to have promising activity.
Unexpected products from the Fp2-catalyzed reductive cyclization of nitroaromatics bearing pendant unsaturation
O'Dell, David K.,Nicholas, Kenneth M.
, p. 747 - 754 (2007/10/03)
A representative o-nitroenone (Z=O) was cyclized by reduction with CO and [CpFe(CO)2]2 (Fp2) as the catalyst to give the corresponding 4-quinolone. In contrast, Baylis-Hillman adducts derived from o-nitrobenzaldehydes were
