N-[(4-Chlorophenyl)methylene]glycine 2-propen-1-yl ester

Base Information

• Chemical Name: N-[(4-Chlorophenyl)methylene]glycine 2-propen-1-yl ester
• CAS No.: 120902-57-0
• Molecular Formula: C₁₂H₁₂ClNO₂
• Molecular Weight: 237.686
• DSSTox Substance ID: DTXSID101200496
• Mol file: 120902-57-0.mol

Synonyms:N-[(4-Chlorophenyl)methylene]glycine 2-propen-1-yl ester;DTXSID101200496;120902-57-0

Chemical Property of N-[(4-Chlorophenyl)methylene]glycine 2-propen-1-yl ester

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 237.0556563
• Heavy Atom Count: 16
• Complexity: 258

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=CCOC(=O)CN=CC1=CC=C(C=C1)Cl

Technology Process of N-[(4-Chlorophenyl)methylene]glycine 2-propen-1-yl ester

There total 1 articles about N-[(4-Chlorophenyl)methylene]glycine 2-propen-1-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glycine allyl ester (59765-55-8) + 4-chlorobenzaldehyde (104-88-1) → {[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-amino}-acetic acid allyl ester (120902-57-0)

Guidance literature:

In dichloromethane; for 3h; Yield given;

DOI:10.1016/S0040-4039(00)80658-9

Reference yield:

{[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-amino}-acetic acid allyl ester (120902-57-0) + methyl iodide (74-88-4) → methyl (E)-2-[(4-chlorobenzylidene)amino]but-3-enoate

Guidance literature:

Multistep reaction;

DOI:10.1016/S0040-4039(00)80658-9

upstream raw materials:

glycine allyl ester

4-chlorobenzaldehyde