CH₃OC₆H₄⁽⁷⁷⁾Br

Base Information

• Chemical Name: CH₃OC₆H₄⁽⁷⁷⁾Br
• CAS No.: 73638-55-8
• Molecular Formula: C₇H₇BrO
• Molecular Weight: 184.132
• Mol file: 73638-55-8.mol

Synonyms:

Chemical Property of CH₃OC₆H₄⁽⁷⁷⁾Br

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CH₃OC₆H₄⁽⁷⁷⁾Br

There total 2 articles about CH₃OC₆H₄⁽⁷⁷⁾Br which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

peracetic acid (79-21-0) + [77Br]bromide (16759-25-4,24959-67-9) + (4-methoxyphenyl)trimethylstannane (940-00-1) → CH3OC6H4(77)Br (73638-55-8) + 1-[77Br]bromo-4-methoxy-benzene (73638-56-9)

Guidance literature:

With dihydrogen peroxide; acetic acid; In acetic acid; addn. of a mixt. of solvent (0.6M MeCO2Na in MeCO2H) and oxidant (in situ generated MeCO3H from 11.4M aq H2O2 and glacial MeCO2H vol. ratio 2:1, kept at room temp. 2 h, prior to application), to dry (77)Br(1-) and tin-compd., stirring, room temp.,30 min; quenching by transferring the vessel contens to 1M aq. NaHSO3 cooled to 0 °C, extn. with CH2Cl2, drying (CaCl2), total yield 28.7%, relative isomeric distribution p:o 90:10%;

Reference yield:

peracetic acid (79-21-0) + [77Br]bromide (16759-25-4,24959-67-9) + (4-methoxyphenyl)trimethylgermane (14476-81-4) → CH3OC6H4(77)Br (73638-55-8) + 1-[77Br]bromo-4-methoxy-benzene (73638-56-9)

Guidance literature:

With dihydrogen peroxide; acetic acid; In acetic acid; addn. of a mixt. of solvent (0.6M MeCO2Na in MeCO2H) and oxidant (in situ generated MeCO3H from 11.4M aq H2O2 and glacial MeCO2H vol. ratio 2:1, kept at room temp. 2 h, prior to application), to dry (77)Br(1-) and Ge-compd., stirring, room temp.,30 min; quenching by transferring the vessel contens to 1M aq. NaHSO3 cooled to 0 °C, extn. with CH2Cl2, drying (CaCl2), total yield 53.9%, relative isomeric distribution p:o 92:2%;

upstream raw materials:

peracetic acid

[⁷⁷Br]bromide

(4-methoxyphenyl)trimethylgermane

(4-methoxyphenyl)trimethylstannane