Technology Process of 8-Benzyl-7-oxo-4,5,7,8,9,10-hexahydro-10aH-thieno<3',2':3,4>pyrido<1,2-c>pyrimidine
There total 4 articles about 8-Benzyl-7-oxo-4,5,7,8,9,10-hexahydro-10aH-thieno<3',2':3,4>pyrido<1,2-c>pyrimidine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
formic acid;
for 14h;
Yield given;
Ambient temperature;
DOI:10.1055/s-1984-31086
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) ethyl carbonochloridate, triethylamine, aq. NaN3 / 1.) acetone, ice cooling, 15 min.; room temp., 1.5 h, 2.) CHCl3, reflux, 14 h
2: 1.) diisobutylaluminum hydride, 2.) 5percent aq. H2SO4 / 1.) toluene, -78 deg C, 50 min.
3: formic acid / 14 h / Ambient temperature
With
formic acid; sodium azide; sulfuric acid; chloroformic acid ethyl ester; diisobutylaluminium hydride; triethylamine;
DOI:10.1055/s-1984-31086
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) ethyl carbonochloridate, triethylamine, aq. NaN3 / 1.) acetone, ice cooling, 15 min.; room temp., 1.5 h, 2.) CHCl3, reflux, 14 h
2: 1.) diisobutylaluminum hydride, 2.) 5percent aq. H2SO4 / 1.) toluene, -78 deg C, 50 min.
3: formic acid / 14 h / Ambient temperature
With
formic acid; sodium azide; sulfuric acid; chloroformic acid ethyl ester; diisobutylaluminium hydride; triethylamine;
DOI:10.1055/s-1984-31086
