5-chloro-2-m-nitrophenylpyrimidine

Base Information

• Chemical Name: 5-chloro-2-m-nitrophenylpyrimidine
• CAS No.: 77139-57-2
• Molecular Formula: C₁₀H₆ClN₃O₂
• Molecular Weight: 235.63
• Mol file: 77139-57-2.mol

Synonyms:

Chemical Property of 5-chloro-2-m-nitrophenylpyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-chloro-2-m-nitrophenylpyrimidine

There total 2 articles about 5-chloro-2-m-nitrophenylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-2-phenylpyrimidine (34771-50-1) → 5-chloro-2-m-nitrophenylpyrimidine (77139-57-2) + 5-chloro-2-o-nitrophenylpyrimidine

Guidance literature:

With sulfuric acid; nitric acid; for 2h; Yield given. Yields of byproduct given;

Reference yield:

2-chloromalonaldehyde (36437-19-1) + 3-nitrobenzamidine hydrochloride (56406-50-9) → 5-chloro-2-m-nitrophenylpyrimidine (77139-57-2)

Guidance literature:

With sodium hydroxide;

DOI:10.1039/jr9510002323

Reference yield:

5-chloro-2-m-nitrophenylpyrimidine (77139-57-2) → 3-(pyrimidin-2-yl)aniline (69491-56-1)

Guidance literature:

With methanol; Pd-BaSO₄; water; Hydrogenation_.Reagens 4: NaOH;

DOI:10.1039/jr9510002323

upstream raw materials:

2-chloromalonaldehyde

3-nitrobenzamidine hydrochloride

5-chloro-2-phenylpyrimidine

Downstream raw materials:

3-(pyrimidin-2-yl)aniline

2-(3-nitrophenyl)pyrimidine