5'-O--5-<3-<<2-<<2-<<(1,1-dimethylethoxy)carbonyl>amino>-3-<1-<(1,1-di-methylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>-amino>ethyl>amino>-3-oxopropyl>-2'-deoxyuridine 3'-(o-chlorophenyl phosphate) triethylamine

Base Information

• Chemical Name: 5'-O--5-<3-<<2-<<2-<<(1,1-dimethylethoxy)carbonyl>amino>-3-<1-<(1,1-di-methylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>-amino>ethyl>amino>-3-oxopropyl>-2'-deoxyuridine 3'-(o-chlorophenyl phosphate) triethylamine
• CAS No.: 132776-89-7
• Molecular Formula: C₆H₁₅N*C₅₇H₆₇ClN₇O₁₆P
• Molecular Weight: 1273.81
• Mol file: 132776-89-7.mol

Synonyms:

Chemical Property of 5'-O--5-<3-<<2-<<2-<<(1,1-dimethylethoxy)carbonyl>amino>-3-<1-<(1,1-di-methylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>-amino>ethyl>amino>-3-oxopropyl>-2'-deoxyuridine 3'-(o-chlorophenyl phosphate) triethylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O--5-<3-<<2-<<2-<<(1,1-dimethylethoxy)carbonyl>amino>-3-<1-<(1,1-di-methylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>-amino>ethyl>amino>-3-oxopropyl>-2'-deoxyuridine 3'-(o-chlorophenyl phosphate) triethylamine

There total 1 articles about 5'-O--5-<3-<<2-<<2-<<(1,1-dimethylethoxy)carbonyl>amino>-3-<1-<(1,1-di-methylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>-amino>ethyl>amino>-3-oxopropyl>-2'-deoxyuridine 3'-(o-chlorophenyl phosphate) triethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5'-O--5-<3-<<2-<<2-<<(2,2-dimethylethoxy)carbonyl>amino>-3-<1-<(2,2-dimethylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>amino>ethyl>amino>-3-oxopropyl>2'-deoxyuridine (128900-35-6) + triethylamine (121-44-8) + 2-chlorophenyl dichlorophosphate (15074-54-1) → 5'-O--5-<3-<<2-<<2-<<(1,1-dimethylethoxy)carbonyl>amino>-3-<1-<(1,1-di-methylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>-amino>ethyl>amino>-3-oxopropyl>-2'-deoxyuridine 3'-(o-chlorophenyl phosphate) triethylamine (132776-89-7)

Guidance literature:

With 1,2,4-Triazole; 1-methyl-1H-imidazole; Yield given. Multistep reaction; 1. CH₃CN, 20 min, RT, 2. CH₃CN, 20 min, RT;

DOI:10.1021/jo00009a044

upstream raw materials:

5'-O--5-<3-<<2-<<2-<<(2,2-dimethylethoxy)carbonyl>amino>-3-<1-<(2,2-dimethylethoxy)carbonyl>-1H-imidazol-4-yl>-1-oxopropyl>amino>ethyl>amino>-3-oxopropyl>2'-deoxyuridine

triethylamine

2-chlorophenyl dichlorophosphate