N-tert-Butyl-N-hydroxycyclohexanamine

Base Information

• Chemical Name: N-tert-Butyl-N-hydroxycyclohexanamine
• CAS No.: 141339-36-8
• Molecular Formula: C10H21NO
• Molecular Weight: 171.283
• DSSTox Substance ID: DTXSID60569204
• Mol file: 141339-36-8.mol

Synonyms:141339-36-8;N-tert-Butyl-N-hydroxycyclohexanamine;DTXSID60569204

Chemical Property of N-tert-Butyl-N-hydroxycyclohexanamine

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 171.162314293
• Heavy Atom Count: 12
• Complexity: 133

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)N(C1CCCCC1)O

Technology Process of N-tert-Butyl-N-hydroxycyclohexanamine

There total 2 articles about N-tert-Butyl-N-hydroxycyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-cyclohexyl-hydroxylamine (2211-64-5) → N-tert-Butyl-N-cyclohexyl-hydroxylamine (141339-36-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Ambient temperature

2: benzene; diethyl ether

In diethyl ether; benzene;

DOI:10.1016/S0040-4039(00)91707-6

Reference yield:

methylmagnesium bromide (75-16-1) + C9H17NO → N-tert-Butyl-N-cyclohexyl-hydroxylamine (141339-36-8)

Guidance literature:

In diethyl ether; benzene;

DOI:10.1016/S0040-4039(00)91707-6

Reference yield: 93.0%

N-tert-Butyl-N-cyclohexyl-hydroxylamine (141339-36-8) → N-(tert-butyl)cyclohexanamine (51609-06-4)

Guidance literature:

With carbon disulfide; In acetonitrile; for 0.0833333h; Ambient temperature;

DOI:10.1016/S0040-4039(00)91706-4

upstream raw materials:

methylmagnesium bromide

N-cyclohexyl-hydroxylamine

Downstream raw materials:

N-(tert-butyl)cyclohexanamine