trans--ethyl 3-(benzyloxy)cyclobutanecarboxylate

Base Information

Chemical Name:trans--ethyl 3-(benzyloxy)cyclobutanecarboxylate
CAS No.:141352-63-8
Molecular Formula:C14H18O3
Molecular Weight:234.29100
Hs Code.:
Mol file:141352-63-8.mol

Synonyms:TRANS-ETHYL 3-(BENZYLOXY)CYCLOBUTANECARBOXYLATE;TRANS--ETHYL3-(BENZYLOXY)CYCLOBUTANECARBOXYLATE;

Suppliers and Price of trans--ethyl 3-(benzyloxy)cyclobutanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of trans--ethyl 3-(benzyloxy)cyclobutanecarboxylate

Chemical Property:

PSA：35.53000
LogP:2.54490

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of trans--ethyl 3-(benzyloxy)cyclobutanecarboxylate

There total 7 articles about trans--ethyl 3-(benzyloxy)cyclobutanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.1%

: 54166-15-3
diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate

: 141352-63-8
1α-benzyloxy-3β-carbethoxy-cyclobutane

: 141352-62-7
ethyl 3α-(benzyloxy)cyclobutane-1α-carboxylate

Guidance literature:: With water; sodium chloride; In dimethyl sulfoxide; at 210 ℃; for 48h;
DOI:10.1002/hlca.19920750216

Reference yield:

: 54307-67-4
1-bromo-2-benzyloxy-3-chloropropane

: 141352-63-8
1α-benzyloxy-3β-carbethoxy-cyclobutane

Guidance literature:: Multi-step reaction with 5 steps

2: aq. 4M KOH / H₂O; ethanol / 5 h / Heating

3: 88.6 percent / 215 °C / 0.4 Torr

4: 99.5 percent / oxalyl chloride / CCl₄ / 1) 0 deg C, 1 h, 2) r.t., 12 h

5: CCl₄ / 5 h / Ambient temperature

With potassium hydroxide; oxalyl dichloride; In tetrachloromethane; ethanol; water;
DOI:10.1002/hlca.19920750216

Reference yield:

: 84182-46-7
3-(benzyloxy)cyclobutane-1,1-dicarboxylic acid

: 141352-63-8
1α-benzyloxy-3β-carbethoxy-cyclobutane

Guidance literature:: Multi-step reaction with 3 steps

1: 88.6 percent / 215 °C / 0.4 Torr

2: 99.5 percent / oxalyl chloride / CCl₄ / 1) 0 deg C, 1 h, 2) r.t., 12 h

3: CCl₄ / 5 h / Ambient temperature

With oxalyl dichloride; In tetrachloromethane;
DOI:10.1002/hlca.19920750216