2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde

Base Information

Chemical Name:2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde
CAS No.:198205-95-7
Molecular Formula:C14H9F3O
Molecular Weight:250.22
Hs Code.:2913000090
European Community (EC) Number:673-277-4
DSSTox Substance ID:DTXSID70362627
Nikkaji Number:J2.042.462A
Wikidata:Q82145886
Mol file:198205-95-7.mol

Synonyms:198205-95-7;2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde;4-[2-(trifluoromethyl)phenyl]benzaldehyde;2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carbaldehyde;2'-Trifluoromethylbiphenyl-4-carbaldehyde;2'-(Trifluoromethyl)biphenyl-4-carbaldehyde;2/'-TRIFLUOROMETHYL-BIPHENYL-4-CARBALDEHYDE;2'-(trifluoromethyl)[1,1'-biphenyl]-4-carbaldehyde;[1,1'-Biphenyl]-4-carboxaldehyde,2'-(trifluoromethyl)-;SCHEMBL566340;DTXSID70362627;AMY33157;AR2075;MFCD01631916;AKOS004116967;DS-0159;2-Trifluoromethylbiphenyl-4-carbaldehyde;4-(2'-trifluoromethylphenyl)benzaldehyde;2'-Trifluoromethyl biphenyl-4-carbaldehyde;2`-Trifluoromethyl-biphenyl-4-carbaldehyde;2'-trifluoromethylbiphenyl-4-carboxaldehyde;BB 0224025;CS-0073674;FT-0643844;EN300-264788;A813968;J-012805;2'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxaldehyde;2'-trifluoromethyl-biphenyl-4-carbaldehyde, AldrichCPR;F9995-2660;[1,1'-Biphenyl]-4-carboxaldehyde, 2'-(trifluoromethyl)-

Suppliers and Price of 2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2'-Trifluoromethylbiphenyl-4-carbaldehyde
250mg
$ 340.00

TRC
2''-(Trifluoromethyl)-[1,1''-biphenyl]-4-carbaldehyde
100mg
$ 60.00

TRC
2''-(Trifluoromethyl)-[1,1''-biphenyl]-4-carbaldehyde
50mg
$ 45.00

SynChem
2'-Trifluoromethyl-biphenyl-4-carbaldehyde 95+%
5 g
$ 275.00

SynChem
2'-Trifluoromethyl-biphenyl-4-carbaldehyde 95+%
1 g
$ 75.00

SynChem
2'-Trifluoromethyl-biphenyl-4-carbaldehyde 95+%
10 g
$ 450.00

Matrix Scientific
2'-Trifluoromethyl-biphenyl-4-carbaldehyde 95+%
10g
$ 1162.00

Matrix Scientific
2'-Trifluoromethyl-biphenyl-4-carbaldehyde 95+%
5g
$ 759.00

Matrix Scientific
2'-Trifluoromethyl-biphenyl-4-carbaldehyde 95+%
1g
$ 185.00

Crysdot
2'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carbaldehyde 97%
5g
$ 142.00

Total 29 raw suppliers

Chemical Property of 2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde

Chemical Property:

Boiling Point:338.8 °C at 760 mmHg
Flash Point:163.3 °C
PSA：17.07000
Density:1.251 g/cm³
LogP:4.18490
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:250.06054939
Heavy Atom Count:18
Complexity:279

Purity/Quality:

97% ^*data from raw suppliers

2'-Trifluoromethylbiphenyl-4-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CC=C(C=C2)C=O)C(F)(F)F

Technology Process of 2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde

There total 4 articles about 2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 392-83-6
o-trifluoromethylphenyl bromide

: 87199-17-5
4-formylphenylboronic acid,

: 198205-95-7
2'-(trifluoromethyl)biphenyl-4-carbaldehyde

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 80 - 100 ℃;

Reference yield: 82.0%

: 392-83-6
o-trifluoromethylphenyl bromide

: 104-88-1
4-chlorobenzaldehyde

: 198205-95-7
2'-(trifluoromethyl)biphenyl-4-carbaldehyde

Guidance literature:: o-trifluoromethylphenyl bromide; With n-butyllithium; Triisopropyl borate; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

4-chlorobenzaldehyde; With potassium phosphate; chloro-(2-dicyclohexylphosphino-2,4,6-triisopropyl-1,1-biphenyl)[2-(2-amino-1,1-biphenyl)]palladium(II); In tetrahydrofuran; hexane; water; at 40 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ol302063g

Reference yield: 42.0%

: 1423-27-4
2-(trifluoromethyl)phenylboronic acid

: 1122-91-4
4-bromo-benzaldehyde

: 198205-95-7
2'-(trifluoromethyl)biphenyl-4-carbaldehyde

Guidance literature:: 2-(trifluoromethyl)phenylboronic acid; 4-bromo-benzaldehyde; With tetrabutylammomium bromide; potassium carbonate; In 1,4-dioxane; water; at 0 ℃; for 0.166667h; Inert atmosphere;

With palladium diacetate; at 70 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm400009c