4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine

Base Information

Chemical Name:4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine
CAS No.:108802-11-5
Molecular Formula:C₆H₁₅N*C₇₁H₉₀ClN₂O₁₆P
Molecular Weight:1395.12
Hs Code.:

4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine

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Chemical Property of 4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine

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Technology Process of 4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine

There total 6 articles about 4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 527-60-6
Mesitol

: 108802-11-5
4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine

Guidance literature:: Multi-step reaction with 3 steps

2: 70 percent / pyridine

3: pyridine

With pyridine;
DOI:10.1016/S0040-4020(01)88067-4

Reference yield:

: 99272-57-8
3-methoxy-1,5-dicarbomethoxy-2-pentene

: 108802-11-5
4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine

Guidance literature:: Multi-step reaction with 3 steps

2: 70 percent / pyridine

3: pyridine

With pyridine;
DOI:10.1016/S0040-4020(01)88067-4

Reference yield:

: 95985-07-2
9-chloro-9-(4-octadecyloxyphenyl)xanthene

: 108802-11-5
4-{(2R,3R,4R,5R)-4-[(2-Chloro-phenoxy)-hydroxy-phosphoryloxy]-5-[9-(4-octadecyloxy-phenyl)-9H-xanthen-9-yloxymethyl]-2-[2-oxo-4-(2,4,6-trimethyl-phenoxy)-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / pyridine

2: pyridine

With pyridine;
DOI:10.1016/S0040-4020(01)88067-4