(4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile

Base Information

• Chemical Name: (4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile
• CAS No.: 860742-62-7
• Molecular Formula: C₁₉H₂₁NO₂
• Molecular Weight: 295.381
• Mol file: 860742-62-7.mol

Synonyms:

Chemical Property of (4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile

There total 4 articles about (4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thymol (89-83-8) → (4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile (860742-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene; hydrogen chloride / Zufuegen von Aluminiumchlorid,weiteren Einleiten von Chlorwasserstoff bei 40-45grad und anschliessenden Kochen mit 10prozentiger Salzsaeure; ist nur als Semicarbazon isoliert

2: absolute alcohol; zinc chloride

With hydrogenchloride; ethanol; zinc(II) chloride; benzene;

Reference yield:

ortho-cresol (95-48-7,77504-84-8) → (4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile (860742-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc cyanide; benzene; hydrogen chloride / 0 °C / anschliessend mit Aluminiumchlorid, weiteres Einleiten von Chlorwasserstoff, zum Schluss bei 50grad, und Zersetzen des Imidhydrochlorids mit siedender verduennter Salzsaeure

2: absolute alcohol; zinc chloride

With zinc(II) cyanide; hydrogenchloride; ethanol; zinc(II) chloride; benzene;

Reference yield:

hydrogen cyanide (74-90-8) + thymol (89-83-8) + 4-hydroxy-3-methyl-benzaldehyde (15174-69-3) → (4-hydroxy-5-isopropyl-2-methyl-phenyl)-(4-hydroxy-3-methyl-phenyl)-acetonitrile (860742-62-7)

Guidance literature:

With ethanol; zinc(II) chloride;

upstream raw materials:

hydrogen cyanide

thymol

4-hydroxy-3-methyl-benzaldehyde

4-formylthymol