3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone)

Base Information

• Chemical Name: 3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone)
• CAS No.: 103100-46-5
• Molecular Formula: C₂₇H₃₆N₄O₅
• Molecular Weight: 496.607
• Mol file: 103100-46-5.mol

Synonyms:

Chemical Property of 3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone)

There total 4 articles about 3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3β-acetoxy-17-hydroxy-5α-pregnan-20-one (5456-44-0) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone) (103100-46-5)

Guidance literature:

With hydrogenchloride; Behandeln der Reaktionsloesung mit Kaliumacetat und wenig Aceton;

DOI:10.1021/jo01372a008

Reference yield:

tigogenin (77-60-1) → 3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone) (103100-46-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ueber 16α,17-Epoxy-3β-hydroxy-5α-pregnan-20-on

2: aq.-ethanolic H₂SO₄

With sulfuric acid;

DOI:10.1002/hlca.19580410622

Reference yield:

isopregnanolone (516-55-2) → 3β-hydroxy-5α-pregn-16-en-20-one-(2,4-dinitro-phenylhydrazone) (103100-46-5)

Guidance literature:

Multi-step reaction with 2 steps

1: mit Hilfe einer Streptomyces-Art

2: aq.-ethanolic H₂SO₄

With sulfuric acid;

DOI:10.1002/hlca.19580410622

upstream raw materials:

3β,16α-dihydroxy-5α-pregnan-20-one

(2,4-dinitro-phenyl)-hydrazine

3β-acetoxy-17-hydroxy-5α-pregnan-20-one

tigogenin