1-(3-Methoxybenzyloxy)adenosine perchlorate

Base Information

• Chemical Name: 1-(3-Methoxybenzyloxy)adenosine perchlorate
• CAS No.: 141776-54-7
• Molecular Formula: C₁₈H₂₁N₅O₆*ClHO₄
• Molecular Weight: 503.853
• Mol file: 141776-54-7.mol

Synonyms:SRI-7055

Chemical Property of 1-(3-Methoxybenzyloxy)adenosine perchlorate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-Methoxybenzyloxy)adenosine perchlorate

There total 2 articles about 1-(3-Methoxybenzyloxy)adenosine perchlorate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

adenosine (58-61-7) → (2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-imino-1-(3-methoxy-benzyloxy)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-3,4-diol; compound with perchloric acid (141776-54-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / m-CPBA / methanol / Ambient temperature

2: 1.) N,N-dimethylacetamide, 2.) NH₄ClO₄ / 1.) 2 h, 2.) H₂O

With ammonium perchlorate; N,N-dimethyl acetamide; 3-chloro-benzenecarboperoxoic acid; In methanol;

DOI:10.1080/07328319808003478

Reference yield:

adenosine 1-oxide (146-92-9,7013-17-4,14215-95-3) + 1-bromomethyl-3-methoxybenzene (874-98-6) → (2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-imino-1-(3-methoxy-benzyloxy)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-3,4-diol; compound with perchloric acid (141776-54-7)

Guidance literature:

With ammonium perchlorate; N,N-dimethyl acetamide; Yield given. Multistep reaction; 1.) 2 h, 2.) H₂O;

DOI:10.1080/07328319808003478

upstream raw materials:

adenosine 1-oxide

1-bromomethyl-3-methoxybenzene

adenosine