(RS,SR)-1-(1-hydroxycyclopentyl)-1-(2-methylphenyl)methanephosphonic acid diethyl

Base Information

• Chemical Name: (RS,SR)-1-(1-hydroxycyclopentyl)-1-(2-methylphenyl)methanephosphonic acid diethyl
• CAS No.: 142474-99-5
• Molecular Formula: C₁₇H₂₇O₄P
• Molecular Weight: 326.373
• Mol file: 142474-99-5.mol

Synonyms:

Chemical Property of (RS,SR)-1-(1-hydroxycyclopentyl)-1-(2-methylphenyl)methanephosphonic acid diethyl

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (RS,SR)-1-(1-hydroxycyclopentyl)-1-(2-methylphenyl)methanephosphonic acid diethyl

There total 1 articles about (RS,SR)-1-(1-hydroxycyclopentyl)-1-(2-methylphenyl)methanephosphonic acid diethyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 2-methylbenzylphosphonate (62778-16-9) + cyclopentanone (120-92-3) → (RS,SR)-1-(1-hydroxycyclopentyl)-1-(2-methylphenyl)methanephosphonic acid diethyl (142474-99-5)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) THF, hexane, -70 deg C, 15 min, 2.) THF, -70 deg C, 15 min;

DOI:10.1007/BF01199525

upstream raw materials:

diethyl 2-methylbenzylphosphonate

cyclopentanone