[6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester

Base Information

• Chemical Name: [6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester
• CAS No.: 199789-51-0
• Molecular Formula: C₃₄H₅₀N₆O₉Si₂
• Molecular Weight: 742.977
• Mol file: 199789-51-0.mol

Synonyms:

Chemical Property of [6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester

There total 3 articles about [6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[O3,O5-bis-(4-methyl-benzoyl)-β-D-erythro-2-deoxy-pentofuranosyl]-6,7-dimethyl-1H-pteridine-2,4-dione (50256-07-0) → [6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester (199789-51-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / P₄S₁₀

2: 91 percent / NH₃

3: 98 percent

4: 80 percent

With tetraphosphorus decasulfide; ammonia;

DOI:10.1080/07328319708006188

Reference yield:

C29H28N4O6S (183279-00-7) → [6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester (199789-51-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 91 percent / NH₃

2: 98 percent

3: 80 percent

With ammonia;

DOI:10.1080/07328319708006188

Reference yield:

4-amino-6,7-dimethyl-1-(2-deoxy-β-D-ribofuranosyl)pteridine-2-one (183279-01-8) → [6,7-Dimethyl-2-oxo-1-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester (199789-51-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent

2: 80 percent

DOI:10.1080/07328319708006188

upstream raw materials:

1-[O³,O⁵-bis-(4-methyl-benzoyl)-β-D-erythro-2-deoxy-pentofuranosyl]-6,7-dimethyl-1H-pteridine-2,4-dione

4-amino-6,7-dimethyl-1-(2-deoxy-β-D-ribofuranosyl)pteridine-2-one

C₂₉H₂₈N₄O₆S

Downstream raw materials:

[1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6,7-dimethyl-2-oxo-1,2-dihydro-pteridin-4-yl]-carbamic acid 2-(4-nitro-phenyl)-ethyl ester

(1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6,7-dimethyl-2-oxo-1,2-dihydro-pteridin-4-yl)-carbamic acid 2-(4-nitro-phenyl)-ethyl ester