1-(2-Amino-5-cyclohexylphenyl)-2-chloroethanone

Base Information

Chemical Name:1-(2-Amino-5-cyclohexylphenyl)-2-chloroethanone
CAS No.:164788-91-4
Molecular Formula:C₁₄H₁₈ClNO
Molecular Weight:251.756
Hs Code.:
DSSTox Substance ID:DTXSID201241239

Synonyms:SCHEMBL8396773;DTXSID201241239;1-(2-amino-5-cyclohexylphenyl)-2-chloroethanone;164788-91-4

Suppliers and Price of 1-(2-Amino-5-cyclohexylphenyl)-2-chloroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(2-Amino-5-cyclohexylphenyl)-2-chloroethanone

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:251.1076919
Heavy Atom Count:17
Complexity:263

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(CC1)C2=CC(=C(C=C2)N)C(=O)CCl

Technology Process of 1-(2-Amino-5-cyclohexylphenyl)-2-chloroethanone

There total 2 articles about 1-(2-Amino-5-cyclohexylphenyl)-2-chloroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6373-50-8
p-cyclohexylaniline

: 107-14-2
chloroacetonitrile

: 164788-91-4
5-cyclohexyl-2-amino-α-chloroacetophenone

Guidance literature:: With aluminium trichloride; boron trichloride; Yield given. Multistep reaction; 1.) dichloromethane, benzene, 5 - 10 deg C, 2.) dichloromethane, benzene, reflux, 20 h;
DOI:10.1016/S0223-5234(96)80002-X

Reference yield:

: 164788-91-4
5-cyclohexyl-2-amino-α-chloroacetophenone

Guidance literature:

Reference yield:

: 164788-91-4
5-cyclohexyl-2-amino-α-chloroacetophenone

: (D,L)-5-cyclohexylkynurenine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) sodium / 1.) ethanol, 45 deg C, 1 h, 2.)a) ethanol, 20 h , RT, b) 40 deg C, 4 h

2: 70 percent / 37percent HCl / 6 h / Heating

With hydrogenchloride; sodium;
DOI:10.1016/S0223-5234(96)80002-X