2-(1-Naphthalenyl)benzaldehyde

Base Information

• Chemical Name: 2-(1-Naphthalenyl)benzaldehyde
• CAS No.: 142598-69-4
• Molecular Formula: C17H12O
• Molecular Weight: 232.282
• Mol file: 142598-69-4.mol

Synonyms:2-(1-Naphthalenyl)benzaldehyde;

Chemical Property of 2-(1-Naphthalenyl)benzaldehyde

Chemical Property:

• Melting Point: 87-88 °C
• Boiling Point: 401.9±24.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.158±0.06 g/cm3(Predicted)
• LogP: 4.31930
• Solubility.: Chloroform, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

2-(1-Naphthalenyl)benzaldehyde 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the preparation of aromatic hydrocarbons, curcumin derivatives as β-secretase inhibitors and other potential antitumor agents.

Technology Process of 2-(1-Naphthalenyl)benzaldehyde

There total 28 articles about 2-(1-Naphthalenyl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-Naphthylboronic acid (13922-41-3) + ortho-bromobenzaldehyde (6630-33-7) → 2-(naphthalene-1-yl)benzaldehyde (142598-69-4)

Guidance literature:

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; dicyclohexyl(1-(naphtho[2,3-b]furan-9-yl)naphthalen-2-yl)phosphine; In toluene; at 80 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c8nj00412a

Reference yield: 98.0%

2-iodobenzaldehyde (26260-02-6) + tri(naphthalen-1-yl)bismuth (33397-22-7) → 2-(naphthalene-1-yl)benzaldehyde (142598-69-4)

Guidance literature:

With potassium phosphate; copper(l) iodide; palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; at 90 ℃; for 3h;

DOI:10.1039/c5ra23311a

Reference yield: 90.0%

1-Bromonaphthalene (90-11-9) + 2-formylbenzene boronic acid (40138-16-7) → 2-(naphthalene-1-yl)benzaldehyde (142598-69-4)

Guidance literature:

With tetrabutylammonium acetate; Pd EnCat 30; In ethanol; at 120 ℃; for 0.333333h; microwave irradiation;

DOI:10.1021/jo701665j

upstream raw materials:

1-Naphthylboronic acid

ortho-bromobenzaldehyde

1-Bromonaphthalene

2-formylbenzene boronic acid

Downstream raw materials:

2-(2-naphthalen-1-yl-phenyl)-oxirane

1-ethynyl-2-(1-naphthyl)-benzene

C₁₈H₁₆O

C₂₃H₁₈O