4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-6-ethyl-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, (R)-

Base Information

Chemical Name:4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-6-ethyl-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, (R)-
CAS No.:108445-56-3
Molecular Formula:C₂₆H₃₁N₃O₃*ClH
Molecular Weight:470.011
Hs Code.:

4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-6-ethyl-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, (R)-

Synonyms:108445-56-3;4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-6-ethyl-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, (R)-;LS-136227

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Chemical Property of 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-6-ethyl-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, (R)-

Chemical Property:

Vapor Pressure:1.39E-14mmHg at 25°C
Boiling Point:604.9°C at 760 mmHg
Flash Point:319.7°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:469.2132196
Heavy Atom Count:33
Complexity:753

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1CC2=CC(=C(C=C2C3=CC(=NC4=C(C=C(C=C4C)C)C)N(C(=O)N13)C)OC)OC.Cl
Isomeric SMILES:CC[C@@H]1CC2=CC(=C(C=C2C3=CC(=NC4=C(C=C(C=C4C)C)C)N(C(=O)N13)C)OC)OC.Cl

Technology Process of 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-6-ethyl-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, (R)-

There total 14 articles about 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-6-ethyl-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88-05-1
2,4,6-trimethylaniline

: 108445-55-2,108445-56-3
6-Ethyl-9,10-dimethoxy-3-methyl-2-[(E)-2,4,6-trimethyl-phenylimino]-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / CHCl₃ / 20 h / Heating

2: K₂CO₃ / acetone / 3 h / Heating

With potassium carbonate; In chloroform; acetone;
DOI:10.1002/hlca.19860690722

Reference yield:

: 94563-91-4
(S)-N-<2-(3,4-Dimethoxyphenyl)-1-ethylethyl>harnstoff

: 108445-55-2,108445-56-3
(S)-6-Ethyl-9,10-dimethoxy-3-methyl-2-[(E)-2,4,6-trimethyl-phenylimino]-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one; hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / Na / ethanol / 20 h / Heating

2: 95 percent / POCl₃ / 24 h / 80 °C

3: 90 percent / CHCl₃ / 20 h / Heating

4: K₂CO₃ / acetone / 3 h / Heating

With sodium; potassium carbonate; trichlorophosphate; In ethanol; chloroform; acetone;
DOI:10.1002/hlca.19860690722

Reference yield:

: 108445-21-2
(R)-N-<2-(3,4-Dimethoxyphenyl)-1-ethylethyl>harnstoff

: 108445-55-2,108445-56-3
(R)-6-Ethyl-9,10-dimethoxy-3-methyl-2-[(E)-2,4,6-trimethyl-phenylimino]-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one; hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / Na / ethanol / 20 h / Heating

2: 95 percent / POCl₃ / 24 h / 80 °C

3: 90 percent / CHCl₃ / 20 h / Heating

4: K₂CO₃ / acetone / 3 h / Heating

With sodium; potassium carbonate; trichlorophosphate; In ethanol; chloroform; acetone;
DOI:10.1002/hlca.19860690722