1-(4-Aminophenyl)piperidin-4-ol

Base Information

Chemical Name:1-(4-Aminophenyl)piperidin-4-ol
CAS No.:142752-12-3
Molecular Formula:C11H16N2O
Molecular Weight:192.261
Hs Code.:2933399090
European Community (EC) Number:827-690-3
DSSTox Substance ID:DTXSID80588573
Wikidata:Q82481326
Mol file:142752-12-3.mol

Synonyms:1-(4-aminophenyl)piperidin-4-ol;142752-12-3;1-(4-AMINOPHENYL)-4-PIPERIDINOL;C11H16N2O;4-(4-hydroxypiperidin-1-yl)aniline;MFCD09738905;1-(4-AMINOPHENYL)-4-HYDROXYPIPERIDINE;SCHEMBL25900;DTXSID80588573;BJXPIIDUCADEKU-UHFFFAOYSA-N;BCP31194;1-(4-amino-phenyl)-piperidin-4-ol;4-(4-hydroxypiperidin-1-yl) aniline;AKOS000147793;4-hydroxy-N-(4-aminophenyl)piperidine;MB07495;MCULE-2154948755;DS-15640;PD129735;SY111065;CS-0095211;EN300-37213;C72677;A885109;Z239873030

Suppliers and Price of 1-(4-Aminophenyl)piperidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(4-Aminophenyl)-4-piperidinol
2.500g
$ 648.00

Matrix Scientific
1-(4-Aminophenyl)-4-piperidinol
1g
$ 285.00

Matrix Scientific
1-(4-Aminophenyl)-4-piperidinol
500mg
$ 185.00

Chemenu
1-(4-aminophenyl)piperidin-4-ol 95+%
1g
$ 267.00

American Custom Chemicals Corporation
1-(4-AMINOPHENYL)PIPERIDIN-4-OL 95.00%
1G
$ 824.25

Ambeed
1-(4-Aminophenyl)piperidin-4-ol 97%
1g
$ 268.00

Ambeed
1-(4-Aminophenyl)piperidin-4-ol 97%
250mg
$ 117.00

Ambeed
1-(4-Aminophenyl)piperidin-4-ol 97%
100mg
$ 78.00

Alichem
1-(4-Aminophenyl)piperidin-4-ol
1g
$ 285.00

AK Scientific
1-(4-Aminophenyl)-4-piperidinol
1g
$ 424.00

Total 16 raw suppliers

Chemical Property of 1-(4-Aminophenyl)piperidin-4-ol

Chemical Property:

Melting Point:158 °C
Boiling Point:404.2±40.0 °C(Predicted)
PKA:14.88±0.20(Predicted)
PSA：49.49000
Density:1.194±0.06 g/cm3(Predicted)
LogP:1.87610
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:192.126263138
Heavy Atom Count:14
Complexity:170

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Aminophenyl)-4-piperidinol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1O)C2=CC=C(C=C2)N

Technology Process of 1-(4-Aminophenyl)piperidin-4-ol

There total 7 articles about 1-(4-Aminophenyl)piperidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 79421-45-7
4-(4-hydroxypiperidinyl)nitrobenzene

: 142752-12-3
4-(4-hydroxypiperidin-1-yl)aniline

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 2h;

Reference yield: 73.4%

: 5382-16-1
4-HYDROXYPIPERIDINE

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 142752-12-3
4-(4-hydroxypiperidin-1-yl)aniline

Guidance literature:: 4-HYDROXYPIPERIDINE; 4-Fluoronitrobenzene; With potassium carbonate; In dimethyl sulfoxide; at 40 ℃; for 3h;

With palladium on activated charcoal; hydrogen; In methanol; at 40 ℃; for 1h;

Reference yield:

: 5382-16-1
4-HYDROXYPIPERIDINE

: 142752-12-3
4-(4-hydroxypiperidin-1-yl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl acetamide / 3 h / 130 °C

2: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 7 h / 20 °C

With hydrogen; potassium carbonate; palladium 10% on activated carbon; In tetrahydrofuran; methanol; N,N-dimethyl acetamide;