5,6-dimethoxy-1H-indole-3-carbaldehyde

Base Information

Chemical Name:5,6-dimethoxy-1H-indole-3-carbaldehyde
CAS No.:142769-27-5
Molecular Formula:C11H11NO3
Molecular Weight:205.21000
Hs Code.:
DSSTox Substance ID:DTXSID00358654
Wikidata:Q82139387
Mol file:142769-27-5.mol

Synonyms:5,6-dimethoxy-1H-indole-3-carbaldehyde;142769-27-5;5,6-dimethoxyindole-3-carboxaldehyde;SCHEMBL3034534;DTXSID00358654;AKOS022258443;5,6-Dimethoxy-1H-indole-3-carboxaldehyde;F15930

Suppliers and Price of 5,6-dimethoxy-1H-indole-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5,6-Dimethoxy-1H-indole-3-carbaldehyde 95%+
1g
$ 556.00

Total 9 raw suppliers

Chemical Property of 5,6-dimethoxy-1H-indole-3-carbaldehyde

Chemical Property:

PSA：51.32000
LogP:1.99760
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:234

Purity/Quality:

97% ^*data from raw suppliers

5,6-Dimethoxy-1H-indole-3-carbaldehyde 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C2C(=C1)C(=CN2)C=O)OC

Technology Process of 5,6-dimethoxy-1H-indole-3-carbaldehyde

There total 7 articles about 5,6-dimethoxy-1H-indole-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 14430-23-0
5,6-dimethoxyindole

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 142769-27-5
5,6-dimethoxy-1H-indole-3-carbaldehyde

Guidance literature:: With trichlorophosphate; at -20 - 0 ℃; for 1h;
DOI:10.1016/j.bmc.2018.07.030

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 142769-27-5
5,6-dimethoxy-1H-indole-3-carbaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: 76 percent / methanol / -10 °C

2: 86 percent / xylene / Heating

3: 85 percent / aq. NaOH / Heating

4: 61 percent / Cu; quinoline / Heating

5: 86 percent / phosphoryl chloride / 0 - 40 °C

With quinoline; sodium hydroxide; copper; trichlorophosphate; In methanol; xylene; 5: Vilsmeier formylation;
DOI:10.1021/jm0493616

Reference yield:

: 157670-07-0
2-azido-3-(3',4'-dimethoxyphenyl)acrylic acid methyl ester

: 142769-27-5
5,6-dimethoxy-1H-indole-3-carbaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 86 percent / xylene / Heating

2: 85 percent / aq. NaOH / Heating

3: 61 percent / Cu; quinoline / Heating

4: 86 percent / phosphoryl chloride / 0 - 40 °C

With quinoline; sodium hydroxide; copper; trichlorophosphate; In xylene; 4: Vilsmeier formylation;
DOI:10.1021/jm0493616