Technology Process of ethyl 4-butyrate
There total 1 articles about ethyl 4-butyrate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; sodium hydride; sodium iodide;
Yield given. Multistep reaction;
1.) RT, 2 h, 2.) 17 h;
DOI:10.1248/cpb.43.256
- Guidance literature:
-
With
iodine; lithium diisopropyl amide;
Yield given. Multistep reaction;
1.) THF, -78 deg C, 30 min, 2.) THF, -78 deg C, 20 min;
DOI:10.1248/cpb.43.256
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) LDA, 2.) I2 / 1.) THF, -78 deg C, 30 min, 2.) THF, -78 deg C, 20 min
2: 1.) NaH, DMSO / 1.) 0 deg C, 5 min, 2.) DMSO, RT, 1.5 h
With
iodine; sodium hydride; dimethyl sulfoxide; lithium diisopropyl amide;
DOI:10.1248/cpb.43.256
