Technology Process of 4,8-bis(dimethylamino)-4,8-diphenylpyrazabole
There total 2 articles about 4,8-bis(dimethylamino)-4,8-diphenylpyrazabole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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In
hexane;
the borane was added to the mixture of sodium pyrazol-1-ylate/hexane under argon, heated until the reaction occurs; evapd. in vac.; extrd. with benzene, partially evapd., ppt. collected, dried in vac.;
- Guidance literature:
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In
hexane; benzene;
byproducts: N,N,N'-trimethylurea; the CH3NCO/hexane soln. was added to the soln. of borane/hexane under argon, heated to 40-50°C, refluxed for 30 min, pyrazole/benzene soln. was added keeping the temp. below 50°C, diluted with hexane, stirred overnight; ppt. was collected, recrystd. from benzene, first fraction is the product, others are contaminated with the urea;
- Guidance literature:
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thermal decompn.;
