Carbamic acid, [(1S,2R)-3-[[[(1,1-dimethylethyl)amino]carbonyl](3-methylbutyl)amino]-2- hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester

Base Information

Chemical Name:Carbamic acid, [(1S,2R)-3-[[[(1,1-dimethylethyl)amino]carbonyl](3-methylbutyl)amino]-2- hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester
CAS No.:143224-67-3
Molecular Formula:C28H41N3O4
Molecular Weight:483.64300
Hs Code.:
Mol file:143224-67-3.mol

Carbamic acid,
[(1S,2R)-3-[[[(1,1-dimethylethyl)amino]carbonyl](3-methylbutyl)amino]-2-
hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester

Synonyms:

Suppliers and Price of Carbamic acid, [(1S,2R)-3-[[[(1,1-dimethylethyl)amino]carbonyl](3-methylbutyl)amino]-2- hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Carbamic acid, [(1S,2R)-3-[[[(1,1-dimethylethyl)amino]carbonyl](3-methylbutyl)amino]-2- hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester

Chemical Property:

PSA：90.90000
LogP:5.52300

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [(1S,2R)-3-[[[(1,1-dimethylethyl)amino]carbonyl](3-methylbutyl)amino]-2- hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester

There total 4 articles about Carbamic acid, [(1S,2R)-3-[[[(1,1-dimethylethyl)amino]carbonyl](3-methylbutyl)amino]-2- hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26049-94-5
(S)-benzyl (4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate

: 143224-67-3
{(1S,2R)-1-Benzyl-3-[3-tert-butyl-1-(3-methyl-butyl)-ureido]-2-hydroxy-propyl}-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 43 percent / NaBH₄ / methanol; tetrahydrofuran

2: 90 percent / KOH / ethanol

3: propan-2-ol / Heating

4: CH₂Cl₂ / Ambient temperature

With potassium hydroxide; sodium tetrahydroborate; In tetrahydrofuran; methanol; ethanol; dichloromethane; isopropyl alcohol;
DOI:10.1021/jm00054a014

Reference yield:

: 128018-43-9
N-benzyloxycarbonyl-3(S)-amino-1-chloro-4-phenyl-2(S)-butanol

: 143224-67-3
{(1S,2R)-1-Benzyl-3-[3-tert-butyl-1-(3-methyl-butyl)-ureido]-2-hydroxy-propyl}-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / KOH / ethanol

2: propan-2-ol / Heating

3: CH₂Cl₂ / Ambient temperature

With potassium hydroxide; In ethanol; dichloromethane; isopropyl alcohol;
DOI:10.1021/jm00054a014

Reference yield:

: 107-85-7
1-amino-3-methylbutane

: 143224-67-3
{(1S,2R)-1-Benzyl-3-[3-tert-butyl-1-(3-methyl-butyl)-ureido]-2-hydroxy-propyl}-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: propan-2-ol / Heating

2: CH₂Cl₂ / Ambient temperature

In dichloromethane; isopropyl alcohol;
DOI:10.1021/jm00054a014