N-(2-benzyloxy-5-bromoacetyl-phenyl)-methanesulfonamide

Base Information

Chemical Name:N-(2-benzyloxy-5-bromoacetyl-phenyl)-methanesulfonamide
CAS No.:14347-25-2
Molecular Formula:C16H16BrNO4S
Molecular Weight:398.277
Hs Code.:
European Community (EC) Number:867-672-2
DSSTox Substance ID:DTXSID40458561
Wikidata:Q82281955

Synonyms:14347-25-2;N-(2-benzyloxy-5-bromoacetyl-phenyl)-methanesulfonamide;N-(2-(benzyloxy)-5-(2-bromoacetyl)phenyl)methanesulfonamide;n-[2-(benzyloxy)-5-(bromoacetyl)phenyl]methanesulfonamide;N-[5-(2-bromoacetyl)-2-phenylmethoxyphenyl]methanesulfonamide;N-[2-(benzyloxy)-5-(2-bromoacetyl)phenyl]methanesulfonamide;SCHEMBL1221632;DTXSID40458561;MSZJJGHZRBKVHQ-UHFFFAOYSA-N;EN300-12638376;N-[5-(bromoacetyl)-2-(phenylmethoxy)phenyl]methanesulphonamide;2-bromo-1-[4-phenylmethoxy-3-[(methylsulfonyl)amino]phenyl]ethanone;2-bromo-1-[4-(phenyl-methoxy)-3-[(methylsulfonyl)amino]phenyl]ethanone

Suppliers and Price of N-(2-benzyloxy-5-bromoacetyl-phenyl)-methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(2-benzyloxy-5-bromoacetyl-phenyl)-methanesulfonamide

Chemical Property:

Vapor Pressure:3.99E-12mmHg at 25°C
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:396.99834
Heavy Atom Count:23
Complexity:485

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)(=O)NC1=C(C=CC(=C1)C(=O)CBr)OCC2=CC=CC=C2

Technology Process of N-(2-benzyloxy-5-bromoacetyl-phenyl)-methanesulfonamide

There total 7 articles about N-(2-benzyloxy-5-bromoacetyl-phenyl)-methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 14347-08-1
1-[4-Phenylmethoxy-3-[(methylsulfonyl)amino]phenyl]ethanone

: 14347-25-2
2-Bromo-1-[4-phenylmethoxy-3-[(methylsulfonyl)amino]phenyl]ethanone

Guidance literature:: With tetra-N-butylammonium tribromide; In tetrahydrofuran; methanol; at 25 ℃; for 1.75h;
DOI:10.1021/op2001904

Reference yield:

: 14347-15-0
1-[4-phenylmethoxy-3-aminophenyl]ethanone

: 14347-25-2
2-Bromo-1-[4-phenylmethoxy-3-[(methylsulfonyl)amino]phenyl]ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / pyridine / CH₂Cl₂

2: 57 percent / CuBr₂ / CHCl₃

With pyridine; copper(ll) bromide; In dichloromethane; chloroform;
DOI:10.1016/S0960-894X(01)00645-X

Reference yield:

: 14347-05-8
4-benzyloxy-3-nitroacetophenone

: 14347-25-2
2-Bromo-1-[4-phenylmethoxy-3-[(methylsulfonyl)amino]phenyl]ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: platinum(IV) oxide; hydrogen / tetrahydrofuran; toluene / 24 h / 25 °C / 772.58 Torr

2: pyridine / acetonitrile / 1 h / 25 °C

3: tetra-N-butylammonium tribromide / tetrahydrofuran; methanol / 1.75 h / 25 °C

With pyridine; platinum(IV) oxide; hydrogen; tetra-N-butylammonium tribromide; In tetrahydrofuran; methanol; toluene; acetonitrile;
DOI:10.1021/op2001904