3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate

Base Information

• Chemical Name: 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate
• CAS No.: 124684-97-5
• Molecular Formula: C₁₁₀H₁₄₃O₁₈P
• Molecular Weight: 1784.31
• Mol file: 124684-97-5.mol

Synonyms:

Chemical Property of 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate

There total 1 articles about 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-di-O-palmitoyl-sn-glycero-benzyloxy (N,N-diisopropylamino) phosphoramidite (120595-85-9,196304-47-9) + 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol (124684-96-4) → 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate (124684-97-5)

Guidance literature:

With 1H-tetrazole; tert.-butylhydroperoxide; Yield given. Multistep reaction; 1.) dichloromethane, acetonitrile, 30 min, 20 deg C, 2.) 0 deg C, 90 min;

DOI:10.1016/S0040-4020(01)81026-7

Reference yield:

3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate (124684-97-5) → 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol phosphate (124684-98-6)

Guidance literature:

With tert-butylamine; for 24h; Heating;

DOI:10.1016/S0040-4020(01)81026-7

upstream raw materials:

1,2-di-O-palmitoyl-sn-glycero-benzyloxy (N,N-diisopropylamino) phosphoramidite

3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol

Downstream raw materials:

3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol phosphate