3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol

Base Information

• Chemical Name: 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol
• CAS No.: 124684-96-4
• Molecular Formula: C₆₈H₇₀O₁₁
• Molecular Weight: 1063.3
• Mol file: 124684-96-4.mol

Synonyms:3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol

Chemical Property of 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol

There total 6 articles about 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-O-allyl-3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol (124684-95-3,132437-49-1,132437-53-7,144068-88-2) → 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol (124684-96-4)

Guidance literature:

1-O-allyl-3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol; With (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; hydrogen; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

With toluene-4-sulfonic acid; In methanol; dichloromethane; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja806283e

Reference yield: 51.0%

3,4,5,6-tetra-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-D-mannopyranosyl)-1-O-p-methoxybenzyl-D-myo-inositol → 3,4,5,6-tetra-O-benzyl-1-O-(2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)-D-myo-inositol + 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol (124684-96-4)

Guidance literature:

With ammonium cerium(IV) nitrate; In water; acetonitrile; at 0 - 20 ℃; for 0.833333h;

DOI:10.1016/j.bmc.2006.04.037

Reference yield:

3,4,5,6-tetra-O-benzyl-1-O-prop-1-enyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol (124778-85-4) → 3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol (124684-96-4)

Guidance literature:

With hydrogenchloride; methanol; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/S0040-4020(01)81026-7

upstream raw materials:

3,4,5,6-tetra-O-benzyl-1-O-prop-1-enyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-D-myo-inositol

benzyl bromide

2-O-acetyl-3,4,6-tri-O-benzyl-α/β-D-mannopyranosyl fluoride

2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl dimethyl phosphite

Downstream raw materials:

triethylammonium 1-O-(6-(S-benzyl)thiohexylphosphonato)-2-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-3,4,5,6-tetra-O-benzyl-D-myo-inositol

3,4,5,6-tetra-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1-O-hexadecanoyl-2-O-hexadecyl-sn-glycero-3-benzylphosphoryl)-D-myo-inositol

3,4,5,6-tetra-O-benzyl inositol

3,4,5,6-tetra-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-palmitoyl-sn-glycero)-D-myo-inositol benzylphosphate