Technology Process of 8-Phenylnaphthalene-2-carboxylic acid
There total 5 articles about 8-Phenylnaphthalene-2-carboxylic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
methanol; water;
at 60 ℃;
for 3h;
Inert atmosphere;
DOI:10.1002/cmdc.201500150
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine / dichloromethane / 16 h / 25 °C / Inert atmosphere
2: [bis(pyridine)iodine]+ tetrafluoroborate; trifluorormethanesulfonic acid / dichloromethane / 22 h / 25 °C / Inert atmosphere
3: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / tetrahydrofuran; water / 110 °C / Inert atmosphere; Microwave irradiation
4: triethylamine; palladium diacetate; 1,3-bis-(diphenylphosphino)propane / dimethyl sulfoxide / 2 h / 70 °C
5: potassium hydroxide / methanol; water / 3 h / 60 °C / Inert atmosphere
With
pyridine; tetrakis(triphenylphosphine) palladium(0); trifluorormethanesulfonic acid; 1,3-bis-(diphenylphosphino)propane; palladium diacetate; sodium carbonate; [bis(pyridine)iodine]+ tetrafluoroborate; triethylamine; potassium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide;
3: |Suzuki Coupling;
DOI:10.1002/cmdc.201500150
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / tetrahydrofuran; water / 110 °C / Inert atmosphere; Microwave irradiation
2: triethylamine; palladium diacetate; 1,3-bis-(diphenylphosphino)propane / dimethyl sulfoxide / 2 h / 70 °C
3: potassium hydroxide / methanol; water / 3 h / 60 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); 1,3-bis-(diphenylphosphino)propane; palladium diacetate; sodium carbonate; triethylamine; potassium hydroxide;
In
tetrahydrofuran; methanol; water; dimethyl sulfoxide;
1: |Suzuki Coupling;
DOI:10.1002/cmdc.201500150