Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-

Base Information

Chemical Name:Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-
CAS No.:146500-63-2
Molecular Formula:C9H4BrF5
Molecular Weight:287.027
Hs Code.:
DSSTox Substance ID:DTXSID90434638
Nikkaji Number:J524.819A
Mol file:146500-63-2.mol

Synonyms:146500-63-2;Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-;DTXSID90434638;1,1,3,3,3-Pentafluoro-2-(4-bromophenyl)-1-propene

Suppliers and Price of Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:285.94165
Heavy Atom Count:15
Complexity:246

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=C(F)F)C(F)(F)F)Br

Technology Process of Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-

There total 5 articles about Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 16184-89-7
4'-bromo-2,2,2-trifluoroacetophenone

: 1895-39-2
sodium chlorodifluoroacetate

: 146500-63-2
1-bromo-4-(perfluoroprop-1-en-2-yl)benzene

Guidance literature:: With triphenylphosphine; In N,N-dimethyl-formamide; at 105 ℃; for 0.5h;
DOI:10.1055/a-1485-4916

Reference yield:

: C₃₄H₃₂N₂O₄

: 431-66-3
2-iodo-1,1,3,3,3-pentafluoropropene

: 589-87-7
1,4-bromoiodobenzene

: 301664-42-6
1-(tert-butyldimethylsilyl)-prop-2-yn-1-ol

: 53243-15-5
2-ethynyl-1H-benzo[d]imidazole

: 10-(4''-(4,6-diphenyl-1,3,5-triazin-2-yl)-[1,1':4',1''-terphenyl]-4-yl)-10H-phenoxazine

: C₄₆H₄₂Br₂N₂O₄

: 146500-63-2
1-bromo-4-(perfluoroprop-1-en-2-yl)benzene

: C₁₅H₂₁BrOSi

Guidance literature:: With chloro-trimethyl-silane; N,N,N,N,-tetramethylethylenediamine; silver; zinc; tetrakis(triphenylphosphine) palladium⁽⁰⁾; Yield given. Multistep reaction; 1) THF, 60 deg C, 9 h, 2) 50 deg C, 5.5 h;
DOI:10.1021/jo00026a028

Reference yield:

: C₃₄H₃₂N₂O₄

: 431-66-3
2-iodo-1,1,3,3,3-pentafluoropropene

: 589-87-7
1,4-bromoiodobenzene

: 301664-42-6
1-(tert-butyldimethylsilyl)-prop-2-yn-1-ol

: 53243-15-5
2-ethynyl-1H-benzo[d]imidazole

: 10-(4''-(4,6-diphenyl-1,3,5-triazin-2-yl)-[1,1':4',1''-terphenyl]-4-yl)-10H-phenoxazine

: C₄₆H₄₂Br₂N₂O₄

: 146500-63-2
1-bromo-4-(perfluoroprop-1-en-2-yl)benzene

: C₁₅H₂₁BrOSi

: C₁₅H₉BrN₂

Guidance literature:: With chloro-trimethyl-silane; N,N,N,N,-tetramethylethylenediamine; silver; zinc; tetrakis(triphenylphosphine) palladium⁽⁰⁾; Yield given. Multistep reaction; 1) THF, 60 deg C, 9 h, 2) 50 deg C, 5.5 h;
DOI:10.1021/jo00026a028