BOC-2-AMINOOCTANOIC ACID

Base Information

• Chemical Name: BOC-2-AMINOOCTANOIC ACID
• CAS No.: 14676-00-7
• Molecular Formula: C₁₃H₂₅NO₄
• Molecular Weight: 259.346
• Hs Code.: 2922499990
• Mol file: 14676-00-7.mol

Synonyms:Octanoic acid,2-[[(1,1-dimethylethoxy)carbonyl]amino];2-(N-Boc)amino-DL-octanoic acid;

Chemical Property of BOC-2-AMINOOCTANOIC ACID

Chemical Property:

• Melting Point: 65-67 °C(Solv: acetonitrile (75-05-8))
• Boiling Point: 389.6±25.0 °C(Predicted)
• PKA: 4.02±0.21(Predicted)
• PSA: 75.63000
• Density: 1.035±0.06 g/cm3(Predicted)
• LogP: 3.32560

Purity/Quality:

98%min ^*data from raw suppliers

Boc-2-aminooctanoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BOC-2-AMINOOCTANOIC ACID

There total 4 articles about BOC-2-AMINOOCTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-aminooctanoic acid (644-90-6,2187-07-7) + di-tert-butyl dicarbonate (24424-99-5) → 2-((tertbutoxycarbonyl)amino)octanoic acid (92211-95-5,92211-96-6,14676-00-7)

Guidance literature:

In 1,4-dioxane;

Reference yield: 84.0%

→ 2-((tertbutoxycarbonyl)amino)octanoic acid (92211-95-5,92211-96-6,14676-00-7) + methyl 2-((tert-butoxycarbonyl)amino)octanoate (87974-78-5)

Guidance literature:

Reference yield: 83.0%

2-aminooctanoic acid (644-90-6,2187-07-7) → 2-((tertbutoxycarbonyl)amino)octanoic acid (92211-95-5,92211-96-6,14676-00-7)

Guidance literature:

In sodium hydroxide; water;

upstream raw materials:

2-aminooctanoic acid

tert-Butyl 4-nitrophenyl carbonate

di-tert-butyl dicarbonate

Downstream raw materials:

tert-butyl (1-((benzyloxy)(3-(dimethylamino)propyl)amino)-1-oxooctan-2-yl)carbamate

tert-butyl (1-((benzyloxy)(2-(dimethylamino)ethyl)amino)-1-oxooctan-2-yl)carbamate

C₄₂H₅₃N₇O₆