Benzenamine, N-butyl-4-iodo-

Base Information

• Chemical Name: Benzenamine, N-butyl-4-iodo-
• CAS No.: 146904-78-1
• Molecular Formula: C10H14IN
• Molecular Weight: 275.132
• Mol file: 146904-78-1.mol

Synonyms:

Chemical Property of Benzenamine, N-butyl-4-iodo-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenamine, N-butyl-4-iodo-

There total 10 articles about Benzenamine, N-butyl-4-iodo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1,4-bromoiodobenzene (589-87-7) + N-butylamine (109-73-9,85404-21-3) → (4-bromo-phenyl)butylamine (81100-29-0) + (R)-1-cyclohexylethylamine (146904-78-1)

Guidance literature:

With copper(l) iodide; cesium acetate; In N,N-dimethyl-formamide; at 20 ℃; Title compound not separated from byproducts;

DOI:10.1021/ol035942y

Reference yield: 76.0%

para-diiodobenzene (624-38-4,1032416-46-8) + N-butylamine (109-73-9,85404-21-3) → (R)-1-cyclohexylethylamine (146904-78-1)

Guidance literature:

With copper(l) iodide; cesium acetate; In dimethyl sulfoxide; at 90 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2008.09.042

Reference yield:

N-butyl-N-(4-iodophenyl)hydrazine (1338369-84-8) → (R)-1-cyclohexylethylamine (146904-78-1)

Guidance literature:

With [Ru(bpyrz)3](PF₆)2*2H₂O; In methanol; acetonitrile; at 20 ℃; for 20h; Air; Visible light; Irradiation;

DOI:10.1055/s-0030-1260082

upstream raw materials:

1,4-bromoiodobenzene

N-butylamine

para-diiodobenzene

tert-butyl 2-(4-iodophenyl)diazene-1-carboxylate

Refernces

• 1、 Komori, Takashi,Satoh, Nobuhiro,Yokoshima, Satoshi,Fukuyama, Tohru. "Copper-mediated aryl amination: In situ generation of an active copper(I) species". experimental part. p. 1859 - 1862. Retrieved 2011/09/15.
• 2、 Kubo, Tetsuji,Katoh, Chiharu,Yamada, Ken,Okano, Kentaro,Tokuyama, Hidetoshi,Fukuyama, Tohru. "A mild inter- and intramolecular amination of aryl halides with a combination of CuI and CsOAc". experimental part. p. 11230 - 11236. Retrieved 2009/04/11.