2-Propenoic acid, 3-phenyl-, 4-formyl-2-methoxyphenyl ester, (2E)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-phenyl-, 4-formyl-2-methoxyphenyl ester, (2E)-
• CAS No.: 147248-48-4
• Molecular Formula: C17H14O4
• Molecular Weight: 282.296
• Mol file: 147248-48-4.mol

Synonyms:4-formyl-2-methoxyphenyl cinnamate;2-Propenoic acid,3-phenyl-,4-formyl-2-methoxyphenyl ester;

Chemical Property of 2-Propenoic acid, 3-phenyl-, 4-formyl-2-methoxyphenyl ester, (2E)-

Chemical Property:

• PSA: 52.60000
• LogP: 3.12650

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 3-phenyl-, 4-formyl-2-methoxyphenyl ester, (2E)-

There total 2 articles about 2-Propenoic acid, 3-phenyl-, 4-formyl-2-methoxyphenyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

vanillin (121-33-5,8014-42-4) + Cinnamoyl chloride (102-92-1,17082-09-6) → (E)-4-methanoyl-2-methoxyphenyl cinnamate (147248-48-4)

Guidance literature:

With pyridine; In dichloromethane; for 1h; Heating;

DOI:10.1007/s11178-005-0283-y

Reference yield: 39.0%

(E)-3-phenylacrylic acid (140-10-3) + vanillin (121-33-5,8014-42-4) → (E)-4-methanoyl-2-methoxyphenyl cinnamate (147248-48-4)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 60 ℃; for 0.75h;

DOI:10.1016/j.bmc.2018.04.007

Reference yield: 90.0%

(E)-4-methanoyl-2-methoxyphenyl cinnamate (147248-48-4) + 1-amino-naphthalene (134-32-7) → 2-methoxy-4-(1-naphthyliminomethyl)phenyl-(E)-3-phenylprop-2-enoate

Guidance literature:

In ethanol; at 20 - 23 ℃;

DOI:10.1134/S1070428006030055

upstream raw materials:

vanillin

Cinnamoyl chloride

(E)-3-phenylacrylic acid