2-(4-Methoxybenzoyl)indan-1,3-dione

Base Information

Chemical Name:2-(4-Methoxybenzoyl)indan-1,3-dione
CAS No.:147847-17-4
Molecular Formula:C17H12O4
Molecular Weight:280.27500
Hs Code.:2914509090
DSSTox Substance ID:DTXSID70371552
Nikkaji Number:J3.479.351D
Wikidata:Q82158915
Mol file:147847-17-4.mol

Synonyms:147847-17-4;2-(4-Methoxybenzoyl)indan-1,3-dione;2-(4'-Methoxybenzoyl)indan-1,3-dione;2-(4-methoxybenzoyl)indene-1,3-dione;2-(4-Methoxybenzoyl)-1H-indene-1,3(2H)-dione;SCHEMBL6970354;DTXSID70371552;NJSFXAKMNPVRCR-UHFFFAOYSA-N;MFCD00129403;AKOS005110812;MS-6343;2-(4-Methoxybenzoyl)indane-1,3-dione;CS-0207109

Suppliers and Price of 2-(4-Methoxybenzoyl)indan-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Methoxybenzoyl)-1H-indene-1,3(2H)-dione
1g
$ 75.00

SynQuest Laboratories
2-(4-Methoxybenzoyl)indane-1,3-dione 98%
10 g
$ 48.00

Crysdot
2-(4-Methoxybenzoyl)-1H-indene-1,3(2H)-dione 95+%
100g
$ 400.00

Apolloscientific
2-(4-Methoxybenzoyl)indane-1,3-dione 98%
10g
$ 44.00

Total 2 raw suppliers

Chemical Property of 2-(4-Methoxybenzoyl)indan-1,3-dione

Chemical Property:

PSA：60.44000
LogP:2.57330
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:280.07355886
Heavy Atom Count:21
Complexity:424

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Methoxybenzoyl)-1H-indene-1,3(2H)-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)C2C(=O)C3=CC=CC=C3C2=O

Technology Process of 2-(4-Methoxybenzoyl)indan-1,3-dione

There total 5 articles about 2-(4-Methoxybenzoyl)indan-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1864-94-4
phenyl formate

: 145291-93-6
1-(2-Iodo-phenyl)-3-(4-methoxy-phenyl)-propane-1,3-dione

: 147847-17-4
2-(4-methoxybenzoyl)-1H-indene-1,3(2H)-dione

Guidance literature:: With dichloro bis(acetonitrile) palladium(II); potassium phosphate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In dimethyl sulfoxide; at 95 ℃; for 24h; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.joc.5b01758

Reference yield: 50.0%

: 131-11-3,64441-70-9
phthalic acid dimethyl ester

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 147847-17-4
2-(4-methoxybenzoyl)-1H-indene-1,3(2H)-dione

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 90 ℃; for 0.333333h;
DOI:10.1021/jm020171+

Reference yield:

: 88-67-5
2-Iodobenzoic acid

: 147847-17-4
2-(4-methoxybenzoyl)-1H-indene-1,3(2H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / 4 h / 80 °C

2.1: lithium hexamethyldisilazane / toluene / 3 h / 0 °C / Inert atmosphere

2.2: 5 h / Inert atmosphere

3.1: dichloro bis(acetonitrile) palladium(II); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; potassium phosphate / dimethyl sulfoxide / 24 h / 95 °C / Sealed tube; Inert atmosphere

With dichloro bis(acetonitrile) palladium(II); potassium phosphate; thionyl chloride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; lithium hexamethyldisilazane; In dimethyl sulfoxide; toluene;
DOI:10.1021/acs.joc.5b01758