Benzenebutanoic acid, 4-(phenylmethyl)-

Base Information

• Chemical Name: Benzenebutanoic acid, 4-(phenylmethyl)-
• CAS No.: 147862-73-5
• Molecular Formula: C17H18O2
• Molecular Weight: 254.329
• Mol file: 147862-73-5.mol

Synonyms:

Chemical Property of Benzenebutanoic acid, 4-(phenylmethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenebutanoic acid, 4-(phenylmethyl)-

There total 7 articles about Benzenebutanoic acid, 4-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4-(diphenylmethylene)-4-oxobutanoic acid (63471-85-2) → 4-(diphenylmethylene)-n-butanoic acid (147862-73-5)

Guidance literature:

With potassium hydroxide; hydrazine; at 180 ℃;

DOI:10.1021/jo981617q

Reference yield:

4-(3-hydroxycarbonylpropyl)-benzophenone (41882-77-3) → 4-(diphenylmethylene)-n-butanoic acid (147862-73-5)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; In diethylene glycol; 1.) 110 deg C, 2 h, 2.) 200 deg C, 8 h;

DOI:10.1021/j150655a041

Reference yield:

methyl 3-(benzyl)propanoate (2046-17-5) → 4-(diphenylmethylene)-n-butanoic acid (147862-73-5)

Guidance literature:

Multi-step reaction with 3 steps

1: AlCl₃ / CH₂Cl₂ / 8 h / Heating

2: 6 M NaOH / 5 h / Heating

3: 90percent hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 1.) 110 deg C, 2 h, 2.) 200 deg C, 8 h

With potassium hydroxide; sodium hydroxide; aluminium trichloride; hydrazine hydrate; In dichloromethane; diethylene glycol;

DOI:10.1021/j150655a041

upstream raw materials:

4-(diphenylmethylene)-4-oxobutanoic acid

4-(3-hydroxycarbonylpropyl)-benzophenone

Diphenylmethane

methyl 3-(benzyl)propanoate

Downstream raw materials:

N,N-dimethyl-4-(diphenylmethylene)-n-butanamine

N,N-dimethyl-4-(diphenylmethylene)-n-butanamide

(+/-)-tetrahydro-2H-pyran-2-ylmethyl 4-(4-benzylphenyl)butanoate

(+/-)-oxiran-2-ylmethyl 4-(4-benzylphenyl)butanoate