7-(t-Butyldiphenylsilyloxy)heptanal

Base Information

Chemical Name:7-(t-Butyldiphenylsilyloxy)heptanal
CAS No.:147974-19-4
Molecular Formula:C23H32O2Si
Molecular Weight:368.591
Hs Code.:
DSSTox Substance ID:DTXSID30447025
Nikkaji Number:J1.575.150I
Wikidata:Q82265801
Mol file:147974-19-4.mol

Synonyms:7-[tert-Butyl(diphenyl)silyl]oxyheptanal;7-(t-butyldiphenylsilyloxy)heptanal;147974-19-4;SCHEMBL4821411;DTXSID30447025;QOWJHQXRFIGPJY-UHFFFAOYSA-N;7-(tert-Butyldiphenylsiloxy)heptanal;A1-05736

Suppliers and Price of 7-(t-Butyldiphenylsilyloxy)heptanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7-(t-Butyldiphenylsilyloxy)heptanal

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:11
Exact Mass:368.217156794
Heavy Atom Count:26
Complexity:372

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCCCCCC=O

Technology Process of 7-(t-Butyldiphenylsilyloxy)heptanal

There total 4 articles about 7-(t-Butyldiphenylsilyloxy)heptanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 191476-08-1
7-((tert-butyldiphenylsilyl)oxy)heptan-1-ol

: 147974-19-4
7-((tert-butyldiphenylsilyl)oxy)heptanal

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 0 ℃; for 2.66667h;
DOI:10.1002/cmdc.202000154

Reference yield: 53.0%

: 22054-13-3
7-hydroxyheptanal

: 58479-61-1
tert-butylchlorodiphenylsilane

: 147974-19-4
7-((tert-butyldiphenylsilyl)oxy)heptanal

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide;
DOI:10.1002/1099-0690(200107)2001:14<2623::aid-ejoc2623>3.0.co;2-1

Reference yield:

: 629-30-1
1,7-heptandiol

: 147974-19-4
7-((tert-butyldiphenylsilyl)oxy)heptanal

Guidance literature:: Multi-step reaction with 2 steps

1: 48 percent / imidazole / tetrahydrofuran / 9 h / 20 °C

2: 90 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / -78 - 0 °C

With 1H-imidazole; oxalyl dichloride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane; 2: Swern oxidation;
DOI:10.1021/ol060221v