[1,1'-Biphenyl]-4-carboxylic acid, 2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-

Base Information

Chemical Name:[1,1'-Biphenyl]-4-carboxylic acid, 2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-
CAS No.:148672-68-8
Molecular Formula:C17H14N2O3
Molecular Weight:294.30500
Hs Code.:
Mol file:148672-68-8.mol

Synonyms:4-(2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl)benzoic acid;2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid;2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-biphenyl-4-carboxylic acid;[1,1'-Biphenyl]-4-carboxylic acid, 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-;2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid;2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl) biphenyl-4-carboxylic acid;

Suppliers and Price of [1,1'-Biphenyl]-4-carboxylic acid, 2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of [1,1'-Biphenyl]-4-carboxylic acid, 2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-

Chemical Property:

PSA：76.22000
LogP:3.71860

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [1,1'-Biphenyl]-4-carboxylic acid, 2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)-

There total 3 articles about [1,1'-Biphenyl]-4-carboxylic acid, 2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 14047-29-1
4-carboxyphenylboronic acid

: 148672-39-3
3-(4'-bromo-3'-methylphenyl)-5-methyl-1,2,4-oxadiazole

: 148672-68-8
2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxylic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water;
DOI:10.1016/j.bmcl.2005.07.085

Reference yield:

: 148672-58-6
4-bromo-N-hydroxy-3-methyl-benzamidine

: 148672-68-8
2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / Pd(PPh₃)4; Na₂CO₃ / 1,2-dimethoxy-ethane; H₂O

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; 2: Suzuki reaction;
DOI:10.1016/j.bmcl.2005.07.085

Reference yield:

: 41963-20-6
4-bromo-3-methylbenzonirtile

: 148672-68-8
2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NH₂OH / methanol

2: 74 percent / Pd(PPh₃)4; Na₂CO₃ / 1,2-dimethoxy-ethane; H₂O

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydroxylamine; sodium carbonate; In methanol; 1,2-dimethoxyethane; water; 3: Suzuki reaction;
DOI:10.1016/j.bmcl.2005.07.085