N-(2-Chlorophenyl)-N-methylformamide

Base Information

• Chemical Name: N-(2-Chlorophenyl)-N-methylformamide
• CAS No.: 14924-76-6
• Molecular Formula: C₈H₈ClNO
• Molecular Weight: 169.611
• DSSTox Substance ID: DTXSID60520052
• Nikkaji Number: J1.989.359F
• Wikidata: Q82383660
• Mol file: 14924-76-6.mol

Synonyms:N-(2-Chlorophenyl)-N-methylformamide;14924-76-6;SCHEMBL2089948;DTXSID60520052

Chemical Property of N-(2-Chlorophenyl)-N-methylformamide

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 169.0294416
• Heavy Atom Count: 11
• Complexity: 140

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C=O)C1=CC=CC=C1Cl

Technology Process of N-(2-Chlorophenyl)-N-methylformamide

There total 3 articles about N-(2-Chlorophenyl)-N-methylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methyl-2-chloroaniline (932-32-1) + formic acid ethyl ester (109-94-4) → formic acid-(2-chloro-N-methyl-anilide) (14924-76-6)

Guidance literature:

at 65 ℃; for 12h; Inert atmosphere;

DOI:10.1039/C9OB00510B

Reference yield:

N-methyl-2-chloroaniline (932-32-1) → formic acid-(2-chloro-N-methyl-anilide) (14924-76-6)

Guidance literature:

Reference yield:

→ formic acid-(2-chloro-N-methyl-anilide) (14924-76-6)

Guidance literature:

DOI:10.1021/jo01265a064

upstream raw materials:

N-methyl-2-chloroaniline

formic acid ethyl ester

Downstream raw materials:

7-chloro-1-methylindoline-2,3-dione