3-Methoxy-4-(2-phenylethoxy)benzaldehyde

Base Information

• Chemical Name: 3-Methoxy-4-(2-phenylethoxy)benzaldehyde
• CAS No.: 149428-74-0
• Molecular Formula: C16H16O3
• Molecular Weight: 256.301
• Hs Code.: 2912499000
• DSSTox Substance ID: DTXSID301274065
• Mol file: 149428-74-0.mol

Synonyms:3-methoxy-4-(2-phenylethoxy)benzaldehyde;149428-74-0;3-Methoxy-4-phenethoxybenzaldehyde;MFCD03270635;Cambridge id 7038937;SCHEMBL9078005;DTXSID301274065;BBL016369;STK398303;AKOS000113390;VS-05302;CS-0314258;AN-023/41116849;SR-01000250208;SR-01000250208-1;3-methoxy-4-(2-phenylethoxy)benzaldehyde, AldrichCPR

Chemical Property of 3-Methoxy-4-(2-phenylethoxy)benzaldehyde

Chemical Property:

• PSA: 35.53000
• LogP: 3.12920
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 256.109944368
• Heavy Atom Count: 19
• Complexity: 261

Purity/Quality:

97% ^*data from raw suppliers

3-methoxy-4-(2-phenylethoxy)benzaldehyde ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1)C=O)OCCC2=CC=CC=C2

Technology Process of 3-Methoxy-4-(2-phenylethoxy)benzaldehyde

There total 4 articles about 3-Methoxy-4-(2-phenylethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

vanillin (121-33-5,8014-42-4) + 1-phenyl-2-bromoethane (103-63-9) → 4-(2-phenylethoxy)-3-methoxybenzaldehyde (149428-74-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 40 - 50 ℃;

DOI:10.1016/j.ejmech.2013.11.001

Reference yield:

C18H20O2 → 3-methoxy-4-phenylethoxyphenyl-1-propanol + 4-(2-phenylethoxy)-3-methoxybenzaldehyde (149428-74-0)

Guidance literature:

With iron(III) sulfate; formic acid; In methanol; at 160 ℃; for 0.833333h; Microwave irradiation;

DOI:10.1039/c5ra26235f

Reference yield:

C18H20O2 → 3-methoxy-4-(2-phenylethoxy)propiophenone + 4-(2-phenylethoxy)-3-methoxybenzaldehyde (149428-74-0)

Guidance literature:

With formic acid; dihydrogen peroxide; In methanol; at 160 ℃; for 0.833333h; Microwave irradiation;

DOI:10.1039/c5ra26235f

upstream raw materials:

vanillin

1-phenyl-2-bromoethane

Downstream raw materials:

(3-methoxy-4-phenethyloxy-phenyl)-methanol

2-(3-methoxy-4-phenethyloxy-phenyl)-N,N-dipropyl-acetamide

3-Methoxy-4-(2-phenylethoxy)phenylacetic acid

4-Chloromethyl-2-methoxy-1-phenethyloxy-benzene