N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-N-methylmethanamine

Base Information

• Chemical Name: N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-N-methylmethanamine
• CAS No.: 14371-17-6
• Molecular Formula: C11H16 N2 O2
• Molecular Weight: 208.26
• NSC Number: 516741
• DSSTox Substance ID: DTXSID50430459
• Mol file: 14371-17-6.mol

Synonyms:NSC516741;14371-17-6;DTXSID50430459;NSC-516741

Chemical Property of N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-N-methylmethanamine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 328.072°C at 760 mmHg
• Flash Point: 152.213°C
• Density: 1.01g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 208.121177757
• Heavy Atom Count: 15
• Complexity: 207

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)N=CC1=CC(=C(C=C1)OC)OC
• Isomeric SMILES: CN(C)/N=C/C1=CC(=C(C=C1)OC)OC

Technology Process of N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-N-methylmethanamine

There total 2 articles about N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-N-methylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,4-dimethoxy-benzaldehyde (120-14-9) + N,N-Dimethylhydrazine (57-14-7) → 3,4-dimethoxybenzaldehyde N,N-dimethylhydrazone (14371-17-6)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/ja300308c

Reference yield:

3,4-dimethoxy-benzaldehyde (120-14-9) + N,N-Dimethylhydrazine (57-14-7) → N'-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-N,N-dimethyl-hydrazine (14371-17-6)

Guidance literature:

In methanol; at 20 ℃; for 0.25h;

DOI:10.1080/00397919808004513

Reference yield: 95.0%

N'-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-N,N-dimethyl-hydrazine (14371-17-6) → veratronitrile (2024-83-1)

Guidance literature:

With potassium carbonate; dimethyl sulfate; for 10h; Heating;

DOI:10.1080/00397919808004513

upstream raw materials:

3,4-dimethoxy-benzaldehyde

N,N-Dimethylhydrazine

Downstream raw materials:

veratronitrile

Refernces

• 1、 Kamal, Ahmed,Arifuddin,Venugopal Rao. "Improved efficient conversion of aldehydes to nitriles via their N,N- dimethyl hydrazones". . p. 4507 - 4512. Retrieved 2007/10/03.