4-(3-Methoxybenzyl)piperidine

Base Information

Chemical Name:4-(3-Methoxybenzyl)piperidine
CAS No.:150019-61-7
Molecular Formula:C13H19NO
Molecular Weight:205.3
Hs Code.:2933399090
European Community (EC) Number:819-408-2
DSSTox Substance ID:DTXSID00588777
Nikkaji Number:J3.289.951J
Wikidata:Q82481682
Mol file:150019-61-7.mol

Synonyms:4-(3-Methoxybenzyl)piperidine;150019-61-7;4-(3-Methoxy-benzyl)-piperidine;4-[(3-Methoxyphenyl)methyl]piperidine;Piperidine, 4-[(3-methoxyphenyl)methyl]-;SCHEMBL3966127;4-(3-methoxy-benzyl)piperidine;DTXSID00588777;VFWKXVIOKYFWIE-UHFFFAOYSA-N;STR08875;MFCD05863572;AKOS011515666;AB22531;DA-17553;C77918;EN300-132335

Suppliers and Price of 4-(3-Methoxybenzyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(3-Methoxybenzyl)piperidine
500mg
$ 165.00

SynQuest Laboratories
4-(3-Methoxybenzyl)piperidine
1 g
$ 560.00

J&W Pharmlab
4-(3-Methoxy-benzyl)-piperidine 98%
5g
$ 1040.00

J&W Pharmlab
4-(3-Methoxy-benzyl)-piperidine 98%
1g
$ 260.00

J&W Pharmlab
4-(3-Methoxy-benzyl)-piperidine 98%
500mg
$ 180.00

Crysdot
4-(3-Methoxybenzyl)piperidine 95+%
1g
$ 347.00

Chemenu
4-(3-methoxybenzyl)piperidine 95%
1g
$ 327.00

American Custom Chemicals Corporation
4-(3-METHOXY-BENZYL)-PIPERIDINE 95.00%
5G
$ 2136.75

American Custom Chemicals Corporation
4-(3-METHOXY-BENZYL)-PIPERIDINE 95.00%
500MG
$ 750.75

Total 17 raw suppliers

Chemical Property of 4-(3-Methoxybenzyl)piperidine

Chemical Property:

Vapor Pressure:0.000274mmHg at 25°C
Boiling Point:322.7oC at 760 mmHg
PKA:10.59±0.10(Predicted)
Flash Point:132.1oC
PSA：21.26000
Density:1.002g/cm3
LogP:2.56610
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:205.146664230
Heavy Atom Count:15
Complexity:177

Purity/Quality:

97% ^*data from raw suppliers

4-(3-Methoxybenzyl)piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)CC2CCNCC2
Uses 4-(3-Methoxy-benzyl)-piperidine is used in the preparation of (3-alkoxybenzyl)piperidine derivatives as melatonergic agents.

Technology Process of 4-(3-Methoxybenzyl)piperidine

There total 5 articles about 4-(3-Methoxybenzyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 35854-37-6
4-(3-methoxybenzyl)pyridine

: 150019-61-7
4-[(3-Methoxyphenyl)methyl]piperidine

Guidance literature:: In water; acetic acid;

Reference yield: 78.0%

: tert-butyl 4-[(3-methoxyphenyl)methyl]piperidine-1-carboxylate

: 150019-61-7
4-[(3-Methoxyphenyl)methyl]piperidine

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 28 ℃; for 1h; Inert atmosphere;

Reference yield:

: 874-98-6
1-bromomethyl-3-methoxybenzene

: 150019-61-7
4-[(3-Methoxyphenyl)methyl]piperidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: toluene / 6 h / 120 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2.2: 1.5 h / 28 °C / Inert atmosphere

3.1: palladium on activated charcoal; hydrogen / ethyl acetate / 2 h / 28 °C / 775.74 Torr / Inert atmosphere

4.1: hydrogenchloride / ethyl acetate / 1 h / 28 °C / Inert atmosphere

With hydrogenchloride; n-butyllithium; palladium on activated charcoal; hydrogen; In tetrahydrofuran; ethyl acetate; toluene;