35854-37-6Relevant articles and documents
Synthesis of 4-benzylpyridines via Pd-catalyzed CH3-arylation of 4-picoline
Wu, Jing,Wang, Dadian,Chen, Xiang,Gui, Qingwen,Li, Hua,Tan, Ze,Huang, Genping,Wang, Guangwei
supporting information, p. 7509 - 7512 (2017/09/27)
A highly efficient synthesis of 4-benzylpyridines was developed via Pd-catalyzed C(sp3)-H arylation between 4-picoline and aryl halides. It was found that the best yields were achieved with a simple Pd(PPh3)4 catalyst and Cs2CO3 as the base. Compared with the known methods, our reaction does not require the use of a strong organometallic reagent as the base.
3-alkoxybenzylpiperidine derivatives as melatonergic agents
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, (2008/06/13)
Novel 3-alkoxybenzylpiperidines have melatonergic properties. They are believed useful in treating depression, jet-lag, work-shift syndrome, sleep disorders, glaucoma, some disorders associated with reproduction, cancer, immune disorders and neuroendocrin
PIPERAZINYL-AND PIPERIDINYL-CYCLOHEXANOLS
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, (2008/06/13)
Novel piperazinyl-and piperidinyl-cyclohexanols of the following formula are useful as anxiolytic agents and have other psychotropic properties STR1
Mercuric acetate cyclization of 4-(arylmethyl)piperidines: Synthesis of indolo[2,3-g]morphans (tetracyclic ring system of strychnos indole alkaloids) and 7,8-benzomorphans
Bosch,Bonjoch,Diez,et al.
, p. 1753 - 1762 (2007/10/02)
A new synthetic route to indolo[2,3-g]morphans and 7,8-benzomorphans is reported. The key step in these syntheses is the mercuric acetate oxidation of appropriate 2-(4-piperidyl-methyl)indoles or 4-benzylpiperidines, respectively. An alternative synthetic
Bridged-ring Nitrogen Compounds. Part 5. Synthesis of 2,6-Methano-3-benzazonine ring-system
Proctor, George R.,Smith, Francis J.
, p. 1754 - 1762 (2007/10/02)
Syntheses of cis- and trans-4-benzyl- and 4-(3-methoxybenzyl)-2-methoxycarbonyl-1-methylpiperidines are described; amino-acids and amino-alcohols obtained from these compounds failed to cyclise. cis-2-Benzyl-4-ethoxycarbonyl-1-methylpiperidine has been ma