Z-Ser-Ala-OH

Base Information

• Chemical Name: Z-Ser-Ala-OH
• CAS No.: 24787-87-9
• Molecular Formula: C14H18 N2 O6
• Molecular Weight: 310.3
• Hs Code.: 2924299090
• Mol file: 24787-87-9.mol

Synonyms:Z-Ser-Ala-OH;24787-87-9;MFCD00238506;DS-3269;C74276;(S)-2-((S)-2-(benzyloxycarbonylamino)-3-hydroxypropanamido)propanoic acid;(2S)-2-[(2S)-2-{[(BENZYLOXY)CARBONYL]AMINO}-3-HYDROXYPROPANAMIDO]PROPANOIC ACID

Chemical Property of Z-Ser-Ala-OH

Chemical Property:

• Vapor Pressure: 2.64E-17mmHg at 25°C
• Boiling Point: 640.9°Cat760mmHg
• Flash Point: 341.4°C
• PSA: 124.96000
• Density: 1.335g/cm³
• LogP: 0.64480
• Storage Temp.: -15°C
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 310.11648630
• Heavy Atom Count: 22
• Complexity: 395

Purity/Quality:

99% ^*data from raw suppliers

Z-Ser-Ala-OH 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)O)NC(=O)C(CO)NC(=O)OCC1=CC=CC=C1
• Isomeric SMILES: C[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)OCC1=CC=CC=C1

Technology Process of Z-Ser-Ala-OH

There total 3 articles about Z-Ser-Ala-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

N-Benzyloxycarbonyl-L-seryl-L-alanin-heptylester (130380-51-7) → N-Benzyloxycarbonyl-L-seryl-L-alanin (24787-87-9)

Guidance literature:

With sodium hydroxide; Na-phosphate buffer; In acetone; for 37h; pH 7.0; Rhizopus niveus lipase;

Reference yield:

methyl ((benzyloxy)carbonyl)-L-seryl-L-alaninate (38428-20-5) → N-Benzyloxycarbonyl-L-seryl-L-alanin (24787-87-9)

Guidance literature:

With sodium hydroxide;

Reference yield:

L-alanin (56-41-7,25191-17-7,18875-37-1) + benzyl (1S)-2-hydrazino-1-(hydroxymethyl)-2-oxoethylcarbamate (26582-86-5) → N-Benzyloxycarbonyl-L-seryl-L-alanin (24787-87-9)

Guidance literature:

Multistep reaction; (i) isopentyl nitrite, aq. HCl, (ii) /BRN= 1720248/, Et₃N;

DOI:10.1021/jm00215a006

upstream raw materials:

methyl ((benzyloxy)carbonyl)-L-seryl-L-alaninate

L-alanin

benzyl (1S)-2-hydrazino-1-(hydroxymethyl)-2-oxoethylcarbamate

N-Benzyloxycarbonyl-L-seryl-L-alanin-heptylester

Downstream raw materials:

Z-Ser-AlaNHNH-Boc

L-ser-L-ala