1,4,6-Trimethylpyridine-2(1H)-one

Base Information

• Chemical Name: 1,4,6-Trimethylpyridine-2(1H)-one
• CAS No.: 15031-89-7
• Molecular Formula: C8H11NO
• Molecular Weight: 137.17900
• Hs Code.: 2933399090
• Mol file: 15031-89-7.mol

Synonyms:1,4,6-trimethylpyridone;1,4,6-Trimethyl-1H-pyridin-2-on;1,4,6-trimethyl-2-pyridone;1,4,6-trimethyl-2-oxo-1-azacyclohexa-3,5-diene;1,4,6-trimethyl-1H-pyridin-2-one;1,4,6-Trimethyl-2-pyridon;

Chemical Property of 1,4,6-Trimethylpyridine-2(1H)-one

Chemical Property:

• PSA: 22.00000
• LogP: 1.00210

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4,6-Trimethylpyridine-2(1H)-one

There total 15 articles about 1,4,6-Trimethylpyridine-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

4,6-dimethyl-2-pyridone (16115-08-5) + methyl iodide (74-88-4) → 1,4,6-trimethyl-1H-pyridin-2-one (15031-89-7)

Guidance literature:

With sodium methylate; In methanol; for 12h; Heating;

DOI:10.1246/bcsj.67.2176

Reference yield:

→ 1,4,6-trimethyl-1H-pyridin-2-one (15031-89-7)

Guidance literature:

With hydrogenchloride; at 160 - 180 ℃;

Reference yield:

→ 1,4,6-trimethyl-1H-pyridin-2-one (15031-89-7)

Guidance literature:

With sulfuric acid; at 160 - 180 ℃;

upstream raw materials:

6-Hydroxy-2,4-lutidin

sodium methylate

methyl iodide

3-acetyl-1,4,6-trimethyl-2-(1H)pyridone

Downstream raw materials:

6-Hydroxy-2,4-lutidin

1,4,6-trimethyl-3-nitro-1H-pyridin-2-one