2-cyano-N-cyclohexyl-N-methylacetamide

Base Information

• Chemical Name: 2-cyano-N-cyclohexyl-N-methylacetamide
• CAS No.: 15059-90-2
• Molecular Formula: C10H16N2O
• Molecular Weight: 180.25
• Mol file: 15059-90-2.mol

Synonyms:

Chemical Property of 2-cyano-N-cyclohexyl-N-methylacetamide

Chemical Property:

Purity/Quality:

2-cyano-N-cyclohexyl-N-methylacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-cyano-N-cyclohexyl-N-methylacetamide

There total 2 articles about 2-cyano-N-cyclohexyl-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methylcyclohexylamine (100-60-7) + ethyl 2-cyanoacetate (105-56-6) → 2-cyano-N-cyclohexyl-N-methyl-acetamide (15059-90-2)

Guidance literature:

In ethanol; Heating;

DOI:10.1021/jm00314a008

Reference yield:

→ 2-cyano-N-cyclohexyl-N-methyl-acetamide (15059-90-2)

Guidance literature:

Cyanessigsaeure-aethylester, Cyclohexyl-methyl-amin;

Reference yield: 55.0%

carbon disulfide (75-15-0,12122-00-8) + 2-cyano-N-cyclohexyl-N-methyl-acetamide (15059-90-2) → 5-amino-N-cyclohexyl-N-methyl-3-thioxo-3H-1,2-dithiole-4-carboxamide

Guidance literature:

With sulfur; sodium hydride; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.2174/1573406416666200909105100

upstream raw materials:

N-methylcyclohexylamine

ethyl 2-cyanoacetate

Downstream raw materials:

3-amino-N-cyclohexyl-N-methyl-propionamide

Refernces